CKD and Health-Related Quality of Life: The Korea National Health and Nutrition Examination Survey.
Am J Kidney Dis
; 67(6): 851-60, 2016 06.
Article
en En
| MEDLINE
| ID: mdl-26706255
ABSTRACT
BACKGROUND:
Quality of life is increasingly viewed as an important health outcome. However, the association of chronic kidney disease (CKD) and its severity with health-related quality of life is uncertain. STUDYDESIGN:
Nationwide population-based cross-sectional study. SETTING &PARTICIPANTS:
46,676 adults participating in the Korea National Health and Nutrition Examination Survey (KNHANES) 2005 to 2013. PREDICTOR CKD ascertained as dipstick-positive proteinuria or estimated glomerular filtration rate (eGFR)<60mL/min/1.73m(2). 5 eGFR categories of CKD were compared ≥90 (with proteinuria), 60 to 89 (with proteinuria), 45 to 59, 30 to 44, and <30mL/min/1.73m(2).OUTCOMES:
The EQ-5D index for health status (range, 0 [death] to 1 [optimal health]).RESULTS:
The total crude CKD prevalence estimate for adults 20 years or older in Korea was 5.5%. After adjustments for age, sex, risk factors, and comorbid conditions, the EQ-5D index was lower in those with versus without CKD, with mean differences of -0.004 (95% CI, -0.015 to 0.007), -0.016 (95% CI, -0.032 to -0.000), -0.020 (95% CI, -0.029 to -0.011), -0.052 (95% CI, -0.072 to -0.032), and -0.067 (95% CI, -0.101 to -0.032), respectively, for CKD eGFR categories of ≥90, 60 to 89, 45 to 59, 30 to 44, and <30mL/min/1.73m(2). In the subgroup of older (≥60 years) individuals, the adjusted mean difference in the EQ-5D index was lower in the CKD eGFR category of 60 to 89mL/min/1.73m(2), but not in the eGFR category of 45 to 59mL/min/1.73m(2), compared to non-CKD.LIMITATIONS:
The survey was conducted on noninstitutionalized civilians, and the chronicity of kidney disease was not verified. Caution is required if our results are applied to special settings and specific populations.CONCLUSIONS:
There was a graded but complex association between CKD and poor health-related quality of life in this large community-based population.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Calidad de Vida
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Insuficiencia Renal Crónica
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Am J Kidney Dis
Año:
2016
Tipo del documento:
Article
País de afiliación:
Corea del Sur