Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors.

Vareslija, Damir; McBryan, Jean; Fagan, Ailís; Redmond, Aisling M; Hao, Yuan; Sims, Andrew H; Turnbull, Arran; Dixon, J M; Ó Gaora, Peadar; Hudson, Lance; Purcell, Siobhan; Hill, Arnold D K; Young, Leonie S

Vareslija, Damir; McBryan, Jean; Fagan, Ailís; Redmond, Aisling M; Hao, Yuan; Sims, Andrew H; Turnbull, Arran; Dixon, J M; Ó Gaora, Peadar; Hudson, Lance; Purcell, Siobhan; Hill, Arnold D K; Young, Leonie S.

Afiliación

Vareslija D; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
McBryan J; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Fagan A; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Redmond AM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
Hao Y; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
Sims AH; University of Edinburgh Cancer Research Centre, Carrington Crescent, Edinburgh, EH4 2XU, United Kingdom.
Turnbull A; University of Edinburgh Cancer Research Centre, Carrington Crescent, Edinburgh, EH4 2XU, United Kingdom.
Dixon JM; University of Edinburgh Cancer Research Centre, Carrington Crescent, Edinburgh, EH4 2XU, United Kingdom.
Ó Gaora P; School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Dublin 4, Ireland.
Hudson L; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Purcell S; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Hill AD; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Young LS; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Ireland. lyoung@rcsi.ie.

Clin Cancer Res ; 22(11): 2765-77, 2016 06 01.

Article en En | MEDLINE | ID: mdl-26763249

Asunto(s)

Antineoplásicos Hormonales/farmacología; Inhibidores de la Aromatasa/farmacología; Neoplasias Encefálicas/metabolismo; Neoplasias de la Mama/metabolismo; Neoplasias Hepáticas/metabolismo; Receptores de Estrógenos/metabolismo; Proteínas Adaptadoras del Transporte Vesicular; Antineoplásicos Hormonales/uso terapéutico; Inhibidores de la Aromatasa/uso terapéutico; Neoplasias Encefálicas/mortalidad; Neoplasias Encefálicas/prevención & control; Neoplasias Encefálicas/secundario; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/mortalidad; Neoplasias de la Mama/patología; Proteínas Portadoras/metabolismo; Resistencia a Antineoplásicos; Proteína 3 de la Respuesta de Crecimiento Precoz/metabolismo; Femenino; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Humanos; Estimación de Kaplan-Meier; Neoplasias Hepáticas/mortalidad; Neoplasias Hepáticas/prevención & control; Neoplasias Hepáticas/secundario; Células MCF-7; Coactivador 3 de Receptor Nuclear/metabolismo; Unión Proteica; Transducción de Señal; Transcriptoma

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Neoplasias de la Mama / Receptores de Estrógenos / Antineoplásicos Hormonales / Inhibidores de la Aromatasa / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Irlanda

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