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Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest.
Sharma, Neha; Kubaczka, Caroline; Kaiser, Stephanie; Nettersheim, Daniel; Mughal, Sadaf S; Riesenberg, Stefanie; Hölzel, Michael; Winterhager, Elke; Schorle, Hubert.
Afiliación
  • Sharma N; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
  • Kubaczka C; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
  • Kaiser S; Institute of Molecular Biology, University of Duisburg-Essen, University Clinics, 45211 Essen, Germany.
  • Nettersheim D; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
  • Mughal SS; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Riesenberg S; Unit for RNA Biology, Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, 53105 Bonn, Germany.
  • Hölzel M; Unit for RNA Biology, Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, 53105 Bonn, Germany.
  • Winterhager E; Institute of Molecular Biology, University of Duisburg-Essen, University Clinics, 45211 Essen, Germany.
  • Schorle H; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany Hubert.Schorle@ukb.uni-bonn.de.
Development ; 143(5): 787-98, 2016 Mar 01.
Article en En | MEDLINE | ID: mdl-26811378

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Gestacionales / Quinasas MAP Reguladas por Señal Extracelular / Proteínas Proto-Oncogénicas c-akt / Inhibidor p21 de las Quinasas Dependientes de la Ciclina / Factor de Transcripción AP-2 Tipo de estudio: Prognostic_studies Límite: Animals / Pregnancy Idioma: En Revista: Development Asunto de la revista: BIOLOGIA / EMBRIOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Gestacionales / Quinasas MAP Reguladas por Señal Extracelular / Proteínas Proto-Oncogénicas c-akt / Inhibidor p21 de las Quinasas Dependientes de la Ciclina / Factor de Transcripción AP-2 Tipo de estudio: Prognostic_studies Límite: Animals / Pregnancy Idioma: En Revista: Development Asunto de la revista: BIOLOGIA / EMBRIOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania