Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide.

Ildefonso, Cristhian J; Jaime, Henrique; Brown, Emily E; Iwata, Ryo L; Ahmed, Chulbul M; Massengill, Michael T; Biswal, Manas R; Boye, Shannon E; Hauswirth, William W; Ash, John D; Li, Qiuhong; Lewin, Alfred S

Ildefonso, Cristhian J; Jaime, Henrique; Brown, Emily E; Iwata, Ryo L; Ahmed, Chulbul M; Massengill, Michael T; Biswal, Manas R; Boye, Shannon E; Hauswirth, William W; Ash, John D; Li, Qiuhong; Lewin, Alfred S.

Afiliación

Ildefonso CJ; Department of Molecular Genetics & Microbiology University of Florida College of Medicine, Gainesville, Florida, United States.
Jaime H; Department of Biology, University of Florida College of Liberal Arts and Sciences, Gainesville, Florida, United States.
Brown EE; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, Florida, United States.
Iwata RL; Department of Molecular Genetics & Microbiology University of Florida College of Medicine, Gainesville, Florida, United States.
Ahmed CM; Department of Molecular Genetics & Microbiology University of Florida College of Medicine, Gainesville, Florida, United States.
Massengill MT; Department of Molecular Genetics & Microbiology University of Florida College of Medicine, Gainesville, Florida, United States.
Biswal MR; Department of Molecular Genetics & Microbiology University of Florida College of Medicine, Gainesville, Florida, United States.
Boye SE; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, Florida, United States.
Hauswirth WW; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, Florida, United States.
Ash JD; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, Florida, United States.
Li Q; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, Florida, United States.
Lewin AS; Department of Molecular Genetics & Microbiology University of Florida College of Medicine, Gainesville, Florida, United States.

Invest Ophthalmol Vis Sci ; 57(2): 372-86, 2016 Feb.

Article en En | MEDLINE | ID: mdl-26842755

Asunto(s)

Péptidos de Penetración Celular/genética; Dependovirus/genética; Factor 2 Relacionado con NF-E2/genética; Retina/metabolismo; Transducción de Señal; Transfección; Animales; Línea Celular; Modelos Animales de Enfermedad; Ensayo de Inmunoadsorción Enzimática; Técnica del Anticuerpo Fluorescente Indirecta; Terapia Genética; Vectores Genéticos; Atrofia Geográfica; Proteínas Fluorescentes Verdes/genética; Humanos; Interleucina-1beta/metabolismo; Péptidos y Proteínas de Señalización Intracelular/genética; Proteína 1 Asociada A ECH Tipo Kelch; Masculino; Ratones; Ratones Endogámicos C57BL; Estrés Oxidativo; Reacción en Cadena en Tiempo Real de la Polimerasa; Epitelio Pigmentado de la Retina/metabolismo; Transgenes; Uveítis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Retina / Transfección / Transducción de Señal / Dependovirus / Factor 2 Relacionado con NF-E2 / Péptidos de Penetración Celular Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Invest Ophthalmol Vis Sci Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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