Constitutively Active MAVS Inhibits HIV-1 Replication via Type I Interferon Secretion and Induction of HIV-1 Restriction Factors.

Gupta, Sachin; Termini, James M; Issac, Biju; Guirado, Elizabeth; Stone, Geoffrey W

Gupta, Sachin; Termini, James M; Issac, Biju; Guirado, Elizabeth; Stone, Geoffrey W.

Afiliación

Gupta S; Department of Microbiology and Immunology, Miami Center for AIDS Research and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Termini JM; Department of Microbiology and Immunology, Miami Center for AIDS Research and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Issac B; Division of Bioinformatics, Biostatistics and Bioinformatics Core, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Guirado E; Department of Microbiology and Immunology, Miami Center for AIDS Research and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Stone GW; Department of Microbiology and Immunology, Miami Center for AIDS Research and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America.

PLoS One ; 11(2): e0148929, 2016.

Article en En | MEDLINE | ID: mdl-26849062

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/fisiología; VIH-1/inmunología; Interferón beta/metabolismo; Proteínas Adaptadoras Transductoras de Señales/genética; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Antígenos CD/metabolismo; Proteínas Ligadas a GPI/metabolismo; Células HEK293; Humanos; Interferón beta/fisiología; Proteínas de Resistencia a Mixovirus/metabolismo; Oxidorreductasas actuantes sobre Donantes de Grupo CH-CH; Proteínas/metabolismo; Proteínas de Unión al ARN; Factores de Transcripción/metabolismo; Regulación hacia Arriba

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: VIH-1 / Interferón beta / Proteínas Adaptadoras Transductoras de Señales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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