TGF-ß1 activates the canonical NF-&#954;B signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.

Ma, Zhen-Yu; Zhong, Zhi-Gang; Qiu, Meng-Yao; Zhong, Yu-Hua; Zhang, Wei-Xi

TGF-ß1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.

Ma, Zhen-Yu; Zhong, Zhi-Gang; Qiu, Meng-Yao; Zhong, Yu-Hua; Zhang, Wei-Xi.

Afiliación

Ma ZY; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong Province, China; Department of Neurology, The Second Affiliated Hospital, Guangzhou Medical University, No.250 Changgang East Road, Guangzhou 510260, Guangdong Provi
Zhong ZG; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong Province, China.
Qiu MY; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong Province, China.
Zhong YH; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong Province, China.
Zhang WX; Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong Province, China. Electronic address: weixizhang@qq.com.

Biochem Biophys Res Commun ; 471(4): 576-81, 2016 Mar 18.

Article en En | MEDLINE | ID: mdl-26874278

Asunto(s)

Apoptosis/efectos de los fármacos; Músculo Esquelético/efectos de los fármacos; Distrofia Muscular de Duchenne/metabolismo; Distrofia Muscular de Duchenne/patología; FN-kappa B/metabolismo; Factor de Crecimiento Transformador beta1/farmacología; Animales; Benzamidas/farmacología; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Fibroblastos/efectos de los fármacos; Fibroblastos/metabolismo; Fibroblastos/patología; Quinasa I-kappa B/antagonistas & inhibidores; Ratones; Ratones Endogámicos C57BL; Músculo Esquelético/metabolismo; Músculo Esquelético/patología; FN-kappa B/genética; ARN Interferente Pequeño/genética; Transducción de Señal/efectos de los fármacos; Factor de Transcripción ReIA/genética; Factor de Transcripción ReIA/metabolismo

Palabras clave

Cell survival; Duchenne muscular dystrophy; Muscle fibroblast; NF-κB; Proliferation; TGF-ß1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: FN-kappa B / Apoptosis / Músculo Esquelético / Distrofia Muscular de Duchenne / Factor de Crecimiento Transformador beta1 Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2016 Tipo del documento: Article

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