Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells.

Suryo Rahmanto, Yohan; Jung, Jin-Gyoung; Wu, Ren-Chin; Kobayashi, Yusuke; Heaphy, Christopher M; Meeker, Alan K; Wang, Tian-Li; Shih, Ie-Ming

Suryo Rahmanto, Yohan; Jung, Jin-Gyoung; Wu, Ren-Chin; Kobayashi, Yusuke; Heaphy, Christopher M; Meeker, Alan K; Wang, Tian-Li; Shih, Ie-Ming.

Afiliación

Suryo Rahmanto Y; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and suryoysr@gmail.com.
Jung JG; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and.
Wu RC; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and the Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan 333, Taiwan, and.
Kobayashi Y; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and the Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Heaphy CM; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and.
Meeker AK; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and.
Wang TL; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and the Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231.
Shih IeM; From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and the Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, shihie@yahoo.com.

J Biol Chem ; 291(18): 9690-9, 2016 Apr 29.

Article en En | MEDLINE | ID: mdl-26953344

Asunto(s)

Regulación Enzimológica de la Expresión Génica; Regulación Neoplásica de la Expresión Génica; Mutación; Neoplasias/metabolismo; Proteínas Nucleares/metabolismo; Telomerasa/biosíntesis; Homeostasis del Telómero; Factores de Transcripción/metabolismo; Transcripción Genética; Proteínas Supresoras de Tumor/metabolismo; Línea Celular Tumoral; Proteínas de Unión al ADN; Histonas/genética; Histonas/metabolismo; Humanos; Neoplasias/genética; Neoplasias/patología; Proteínas Nucleares/genética; Proteínas Represoras/genética; Proteínas Represoras/metabolismo; Complejo Correpresor Histona Desacetilasa y Sin3; Telomerasa/genética; Factores de Transcripción/genética; Proteínas Supresoras de Tumor/genética

Palabras clave

ARID1A; chromatin remodeling; ovarian cancer; telomerase reverse transcriptase (TERT); telomere; tumor suppressor gene

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Transcripción Genética / Proteínas Nucleares / Regulación Enzimológica de la Expresión Génica / Regulación Neoplásica de la Expresión Génica / Telomerasa / Proteínas Supresoras de Tumor / Homeostasis del Telómero / Mutación / Neoplasias Límite: Humans Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article

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