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Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.
Kurihara, Toshihide; Westenskow, Peter D; Gantner, Marin L; Usui, Yoshihiko; Schultz, Andrew; Bravo, Stephen; Aguilar, Edith; Wittgrove, Carli; Friedlander, Mollie Sh; Paris, Liliana P; Chew, Emily; Siuzdak, Gary; Friedlander, Martin.
Afiliación
  • Kurihara T; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Westenskow PD; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Gantner ML; The Lowy Medical Research Institute, La Jolla, United States.
  • Usui Y; The Lowy Medical Research Institute, La Jolla, United States.
  • Schultz A; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Bravo S; Center for Metabolomics, The Scripps Research Institute, La Jolla, United States.
  • Aguilar E; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Wittgrove C; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Friedlander MSh; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Paris LP; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Chew E; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States.
  • Siuzdak G; National Eye Institute, National Institutes of Health, Bethesda, United States.
  • Friedlander M; Center for Metabolomics, The Scripps Research Institute, La Jolla, United States.
Elife ; 52016 03 15.
Article en En | MEDLINE | ID: mdl-26978795
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Fotorreceptoras / Estrés Fisiológico / Células Epiteliales / Epitelio Pigmentado de la Retina / Degeneración Macular / Hipoxia Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Elife Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Fotorreceptoras / Estrés Fisiológico / Células Epiteliales / Epitelio Pigmentado de la Retina / Degeneración Macular / Hipoxia Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Elife Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos