N-Acetylcysteine in the treatment of trichotillomania: remarkable results in two patients.
J Eur Acad Dermatol Venereol
; 30(9): 1606-8, 2016 Sep.
Article
en En
| MEDLINE
| ID: mdl-27146087
ABSTRACT
BACKGROUND:
The management of trichotillomania is challenging. The limited efficacy and side-effects of pharmacological medications and difficulty in long-term maintenance of behavioural therapies necessitates alternative treatment options. A dysregulated glutamatergic system has been implicated in the pathophysiology of trichotillomania. A limited number of reports indicate that N-acetylcysteine (NAC), a glutamate modulator, may be a promising treatment for this disorder.OBJECTIVES:
We report two patients with trichotillomania for whom treatment with NAC was successful.METHODS:
The first patient was a 30-year-old female, and the second patient was a 14-year-old girl, both who were diagnosed with trichotillomania and prescribed NAC (1200 mg/d, p.o.).RESULTS:
Hair pulling behaviour subsided within 2 months and 2 weeks of initiating NAC in the first and second patient, respectively. Complete hair regrowth was observed after 4 and 6 months of NAC treatment in the first and second patient, respectively. No side-effects related to NAC were noted.CONCLUSION:
NAC could be a well-tolerated and effective treatment option for trichotillomania.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Acetilcisteína
/
Tricotilomanía
Límite:
Adolescent
/
Adult
/
Female
/
Humans
Idioma:
En
Revista:
J Eur Acad Dermatol Venereol
Asunto de la revista:
DERMATOLOGIA
/
DOENCAS SEXUALMENTE TRANSMISSIVEIS
Año:
2016
Tipo del documento:
Article
País de afiliación:
Turquía