DyNet: visualization and analysis of dynamic molecular interaction networks.
Bioinformatics
; 32(17): 2713-5, 2016 09 01.
Article
en En
| MEDLINE
| ID: mdl-27153624
ABSTRACT
UNLABELLED The ability to experimentally determine molecular interactions on an almost proteome-wide scale under different conditions is enabling researchers to move from static to dynamic network analysis, uncovering new insights into how interaction networks are physically rewired in response to different stimuli and in disease. Dynamic interaction data presents a special challenge in network biology. Here, we present DyNet, a Cytoscape application that provides a range of functionalities for the visualization, real-time synchronization and analysis of large multi-state dynamic molecular interaction networks enabling users to quickly identify and analyze the most 'rewired' nodes across many network states. AVAILABILITY AND IMPLEMENTATION DyNet is available at the Cytoscape (3.2+) App Store (http//apps.cytoscape.org/apps/dynet). CONTACT david.lynn@sahmri.com SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Programas Informáticos
/
Biología Computacional
/
Redes Reguladoras de Genes
Límite:
Humans
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Australia