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Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in mice.
Dovey, Oliver M; Chen, Bin; Mupo, Annalisa; Friedrich, Mathias; Grove, Carolyn S; Cooper, Jonathan L; Lee, Benjamin; Varela, Ignacio; Huang, Yue; Vassiliou, George S.
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  • Dovey OM; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK od2@sanger.ac.uk gsv20@sanger.ac.uk.
  • Chen B; Department of Medical Genetics, School of Basic Medicine, Peking Union Medical College, Beijing, China State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China Department of Haematology, Cambridge University Hospitals
  • Mupo A; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
  • Friedrich M; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
  • Grove CS; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Australia PathWest Division of Clinical Pathology, Queen Elizabeth II Medical Centre, Nedlands, Australia.
  • Cooper JL; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
  • Lee B; Takeda Pharmaceuticals International, Cambridge, MA, USA.
  • Varela I; Instituto de Biomedicina y Biotecnología de Cantabria, Santander, Spain.
  • Huang Y; Department of Medical Genetics, School of Basic Medicine, Peking Union Medical College, Beijing, China State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China.
  • Vassiliou GS; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK Department of Haematology, Cambridge University Hospitals NHS Trust, UK od2@sanger.ac.uk gsv20@sanger.ac.uk.
Haematologica ; 101(8): e328-31, 2016 08.
Article en En | MEDLINE | ID: mdl-27175030
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a Medicamentos / Leucemia Mieloide Aguda / Mutación de Línea Germinal / Tirosina Quinasa 3 Similar a fms Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Haematologica Año: 2016 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a Medicamentos / Leucemia Mieloide Aguda / Mutación de Línea Germinal / Tirosina Quinasa 3 Similar a fms Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Haematologica Año: 2016 Tipo del documento: Article