Cerebral Venous Sinus Thrombosis Involving the Straight Sinus May Result in Infarction and/or Hemorrhage.

ABSTRACT

AIM: We retrospectively investigated the clinical profiles and neuroimaging data of patients with documented cerebral venous sinus thrombosis (CVST) to analyze the relationship between the sites of CVST and clinical manifestations. METHODS: A total of 68 patients, who were examined and treated at our hospital, were identified after review and their data were retrospectively analyzed. RESULTS: Initial non-contrast CT scan showed a definite spontaneous hyperdensity of one or several sinuses in 47 patients (69.1%) and was normal in the remaining patients (30.9%). Furthermore, the x03C7;2 test revealed a significant difference (p = 0.001) in the infarction or hemorrhage rate between the patients with straight sinus thrombosis (SST; 19 of 28, 67.8%) and other subjects (9 of 39, 23.1%). Moreover, patients with SST had a 6.33-fold (95% CI 2.18-18.4) increased risk of infarction or hemorrhage. CONCLUSION: Our data suggested that infarction and/or hemorrhage was more common in CVST patients with SST.