Age-related decline in skeletal muscle mass and function among elderly men and women in Shanghai, China: a cross sectional study.
Asia Pac J Clin Nutr
; 25(2): 326-32, 2016.
Article
en En
| MEDLINE
| ID: mdl-27222416
ABSTRACT
OBJECTIVE:
To investigate the relationship of muscle mass and muscle function with age. METHODS AND STUDYDESIGN:
The study including 415 participants (aged 60-99 years). Upper (UMM) and lower (LMM) limbs muscle mass and whole body fat free mass (FFM) were measured by bioelectrical impedance analysis. The appendicular skeletal muscle mass (ASM) index (ASM/height2) was calculated. Muscle function was assessed by measuring hand grip strength (HGS) and gait speed.RESULTS:
Using ASM index cutoff values we found that higher prevalence of sarcopenia in women than in men (33.5% vs 23.6%, p=0.025). In the upper limb, HGS (ß=-0.809) declined more rapidly with age than did UMM (ß=-0.592) in men, but not in women (ß=-0.389 and ß=-0.486 respectively). In the lower limb, gait speed declined more rapidly than LMM in both men (ß=-0.683 vs ß=-0.442) and women (ß=-1.00 vs ß=-0.461). The variance of UMM explained 28-29% of the variance of HGS, and LMM explained 7-8% of the variance of gait speed in women and men respectively. In addition to the common predictors (BMI and age), the specific predictors were smoking, exercise and education for FFM and ASM, and smoking, drinking and exercise for HGS (p<0.05).CONCLUSIONS:
Loss of muscle function is greater than the decline of muscle mass particularly in the upper limbs in men. However, women are more prone to have low muscle mass than the men. Exercise programs need to be designed gender specifically.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Músculo Esquelético
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Sarcopenia
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
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Risk_factors_studies
Límite:
Aged
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Aged80
/
Female
/
Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Asia Pac J Clin Nutr
Asunto de la revista:
CIENCIAS DA NUTRICAO
Año:
2016
Tipo del documento:
Article
País de afiliación:
China