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IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma.
Svalina, Matthew N; Kikuchi, Ken; Abraham, Jinu; Lal, Sangeet; Davare, Monika A; Settelmeyer, Teagan P; Young, Michael C; Peckham, Jennifer L; Cho, Yoon-Jae; Michalek, Joel E; Hernandez, Brian S; Berlow, Noah E; Jackson, Melanie; Guillaume, Daniel J; Selden, Nathan R; Bigner, Darell D; Nazemi, Kellie J; Green, Sarah C; Corless, Christopher L; Gultekin, Sakir; Mansoor, Atiya; Rubin, Brian P; Woltjer, Randall; Keller, Charles.
Afiliación
  • Svalina MN; Children's Cancer Therapy Development Institute, Beaverton, OR USA.
  • Kikuchi K; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Abraham J; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Lal S; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Davare MA; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Settelmeyer TP; Children's Cancer Therapy Development Institute, Beaverton, OR USA.
  • Young MC; Children's Cancer Therapy Development Institute, Beaverton, OR USA.
  • Peckham JL; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Cho YJ; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Michalek JE; Division of Child Neurology, Stanford Medicine Cancer Institute, Palo Alto, CA 94304 USA.
  • Hernandez BS; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX 78229 USA.
  • Berlow NE; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX 78229 USA.
  • Jackson M; Children's Cancer Therapy Development Institute, Beaverton, OR USA.
  • Guillaume DJ; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Selden NR; Division of Pediatric Neurosurgery, Department of Neurological Surgery, Oregon Health &Science University, Portland, OR 97239 USA.
  • Bigner DD; Division of Pediatric Neurosurgery, Department of Neurological Surgery, Oregon Health &Science University, Portland, OR 97239 USA.
  • Nazemi KJ; Pediatric Brain Tumor Foundation Institute at Duke, Duke University Medical Center, Durham, NC 27705 USA.
  • Green SC; Department of Pediatrics, Oregon Health &Science University, Portland, OR 97239 USA.
  • Corless CL; Department of Pathology, Oregon Health &Science University, Portland, OR 97239 USA.
  • Gultekin S; Department of Pathology, Oregon Health &Science University, Portland, OR 97239 USA.
  • Mansoor A; Department of Pathology, Oregon Health &Science University, Portland, OR 97239 USA.
  • Rubin BP; Department of Pathology, Oregon Health &Science University, Portland, OR 97239 USA.
  • Woltjer R; Departments of Anatomic Pathology and Molecular Genetics, Taussig Cancer Center and Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195 USA.
  • Keller C; Department of Pathology, Oregon Health &Science University, Portland, OR 97239 USA.
Sci Rep ; 6: 27012, 2016 06 03.
Article en En | MEDLINE | ID: mdl-27255663
Asunto(s)
Neoplasias Cerebelosas/líquido cefalorraquídeo; Meduloblastoma/líquido cefalorraquídeo; Neoplasias Meníngeas/líquido cefalorraquídeo; Receptores de Somatomedina/metabolismo; Adolescente; Antineoplásicos/farmacología; Biomarcadores de Tumor/antagonistas & inhibidores; Biomarcadores de Tumor/líquido cefalorraquídeo; Biomarcadores de Tumor/genética; Estudios de Casos y Controles; Adhesión Celular; Línea Celular Tumoral; Movimiento Celular; Proliferación Celular; Neoplasias Cerebelosas/tratamiento farmacológico; Neoplasias Cerebelosas/patología; Niño; Ensayos de Selección de Medicamentos Antitumorales; Femenino; Expresión Génica; Humanos; Concentración 50 Inhibidora; Proteína 3 de Unión a Factor de Crecimiento Similar a la Insulina/líquido cefalorraquídeo; Proteína 3 de Unión a Factor de Crecimiento Similar a la Insulina/genética; Factor I del Crecimiento Similar a la Insulina/líquido cefalorraquídeo; Factor I del Crecimiento Similar a la Insulina/genética; Masculino; Metaloproteinasa 9 de la Matriz/líquido cefalorraquídeo; Metaloproteinasa 9 de la Matriz/genética; Meduloblastoma/tratamiento farmacológico; Meduloblastoma/secundario; Neoplasias Meníngeas/tratamiento farmacológico; Neoplasias Meníngeas/secundario; Terapia Molecular Dirigida; Inhibidor 1 de Activador Plasminogénico/líquido cefalorraquídeo; Inhibidor 1 de Activador Plasminogénico/genética; Receptor IGF Tipo 1; Receptores de Somatomedina/antagonistas & inhibidores; Receptores de Somatomedina/genética; Inhibidor Tisular de Metaloproteinasa-1/líquido cefalorraquídeo; Inhibidor Tisular de Metaloproteinasa-1/genética
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Receptores de Somatomedina / Meduloblastoma / Neoplasias Meníngeas Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Receptores de Somatomedina / Meduloblastoma / Neoplasias Meníngeas Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article