Pediatric Malignant Bone Tumors: A Review and Update on Current Challenges, and Emerging Drug Targets.
Curr Probl Pediatr Adolesc Health Care
; 46(7): 213-228, 2016 Jul.
Article
en En
| MEDLINE
| ID: mdl-27265835
ABSTRACT
Osteosarcoma (OS) and the Ewing sarcoma family of tumors (ESFT) are the most common malignant bone tumors in children and adolescents. While significant improvements in survival have been seen in other pediatric malignancies the treatment and prognosis for pediatric bone tumors has remained unchanged for the past 3 decades. This review and update of pediatric malignant bone tumors will provide a general overview of osteosarcoma and the Ewing sarcoma family of tumors, discuss bone tumor genomics, current challenges, and emerging drug targets.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Óseas
/
Osteosarcoma
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Límite:
Child
/
Humans
Idioma:
En
Revista:
Curr Probl Pediatr Adolesc Health Care
Asunto de la revista:
PEDIATRIA
/
SERVICOS DE SAUDE
Año:
2016
Tipo del documento:
Article