Microvascular endothelial cells-derived microvesicles imply in ischemic stroke by modulating astrocyte and blood brain barrier function and cerebral blood flow.

Pan, Qunwen; He, Caixia; Liu, Hua; Liao, Xiaorong; Dai, Bingyan; Chen, Yanfang; Yang, Yi; Zhao, Bin; Bihl, Ji; Ma, Xiaotang

Pan, Qunwen; He, Caixia; Liu, Hua; Liao, Xiaorong; Dai, Bingyan; Chen, Yanfang; Yang, Yi; Zhao, Bin; Bihl, Ji; Ma, Xiaotang.

Afiliación

Pan Q; Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.
He C; Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.
Liu H; Guangdong Medical University, Zhanjiang, 524001, China.
Liao X; College of Health Science, Wuhan Sports University, Wuhan, Hubei, 430000, China.
Dai B; Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.
Chen Y; Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.
Yang Y; Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.
Zhao B; Department of Pharmacology and Toxicology, Wright State University, Dayton, OH, 45435, USA.
Bihl J; Department of Neurology, Boonshoft School of Medicine, Wright State University, Dayton, OH, 45435, USA.
Ma X; College of Health Science, Wuhan Sports University, Wuhan, Hubei, 430000, China.

Mol Brain ; 9(1): 63, 2016 06 07.

Article en En | MEDLINE | ID: mdl-27267759

Asunto(s)

Astrocitos/metabolismo; Barrera Hematoencefálica/fisiopatología; Isquemia Encefálica/fisiopatología; Micropartículas Derivadas de Células/metabolismo; Circulación Cerebrovascular; Células Endoteliales/metabolismo; Microvasos/patología; Accidente Cerebrovascular/fisiopatología; Animales; Apoptosis; Barrera Hematoencefálica/patología; Isquemia Encefálica/complicaciones; Isquemia Encefálica/patología; Caspasa 9/metabolismo; Claudina-5/metabolismo; Citometría de Flujo; Glucosa/deficiencia; Humanos; Infarto de la Arteria Cerebral Media/complicaciones; Infarto de la Arteria Cerebral Media/patología; Masculino; Ratones Endogámicos C57BL; Oxígeno; Permeabilidad; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Accidente Cerebrovascular/complicaciones; Accidente Cerebrovascular/patología; Proteína de la Zonula Occludens-1/metabolismo

Palabras clave

Astrocytes; Blood brain barrier; Cerebral blood flow; Cerebral ischemia; Endothelial cells; Gene expression; Microvesicles

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Barrera Hematoencefálica / Isquemia Encefálica / Circulación Cerebrovascular / Astrocitos / Accidente Cerebrovascular / Células Endoteliales / Microvasos / Micropartículas Derivadas de Células Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Mol Brain Asunto de la revista: BIOLOGIA MOLECULAR / CEREBRO Año: 2016 Tipo del documento: Article País de afiliación: China

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google