Polymerase Î¸ is a robust terminal transferase that oscillates between three different mechanisms during end-joining.

Kent, Tatiana; Mateos-Gomez, Pedro A; Sfeir, Agnel; Pomerantz, Richard T

Kent, Tatiana; Mateos-Gomez, Pedro A; Sfeir, Agnel; Pomerantz, Richard T.

Afiliación

Kent T; Fels Institute for Cancer Research, Temple University Lewis Katz School of Medicine, Philadelphia, United States.
Mateos-Gomez PA; Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, Philadelphia, United States.
Sfeir A; Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, United States.
Pomerantz RT; Department of Cell Biology, New York University School of Medicine, New York, United States.

Elife ; 52016 06 17.

Article en En | MEDLINE | ID: mdl-27311885

Asunto(s)

Reparación del ADN por Unión de Extremidades; ADN Nucleotidilexotransferasa/metabolismo; ADN Polimerasa Dirigida por ADN/metabolismo; ADN/metabolismo; Animales; Coenzimas/metabolismo; Células Madre Embrionarias; Manganeso/metabolismo; Ratones; ADN Polimerasa theta

Palabras clave

DNA polymerase; DNA repair; alternative end-Joining; biochemistry; chromosomes; genes; genetic diversity; genetic instability; human; microhomology-mediated end-joining; mouse

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN / ADN Nucleotidilexotransferasa / ADN Polimerasa Dirigida por ADN / Reparación del ADN por Unión de Extremidades Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Elife Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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