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Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele Carriers.
Abdelhady, Ahmed M; Shugg, Tyler; Thong, Nancy; Lu, Jessica Bo Li; Kreutz, Yvonne; Jaynes, Heather A; Robarge, Jason D; Tisdale, James E; Desta, Zeruesenay; Overholser, Brian R.
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  • Abdelhady AM; Department of Pharmacy Practice, College of Pharmacy, Purdue University, West Lafayette.
  • Shugg T; Department of Pharmacy Practice, College of Pharmacy, Purdue University, West Lafayette.
  • Thong N; Division of Clinical Pharmacology, School of Medicine, Indiana University, Indianapolis, Indiana, USA.
  • Lu JB; Division of Clinical Pharmacology, School of Medicine, Indiana University, Indianapolis, Indiana, USA.
  • Kreutz Y; Division of Clinical Pharmacology, School of Medicine, Indiana University, Indianapolis, Indiana, USA.
  • Jaynes HA; Department of Pharmacy Practice, College of Pharmacy, Purdue University, West Lafayette.
  • Robarge JD; Division of Clinical Pharmacology, School of Medicine, Indiana University, Indianapolis, Indiana, USA.
  • Tisdale JE; Department of Pharmacy Practice, College of Pharmacy, Purdue University, West Lafayette.
  • Desta Z; Division of Clinical Pharmacology, School of Medicine, Indiana University, Indianapolis, Indiana, USA.
  • Overholser BR; Division of Clinical Pharmacology, School of Medicine, Indiana University, Indianapolis, Indiana, USA.
J Cardiovasc Electrophysiol ; 27(10): 1206-1213, 2016 10.
Article en En | MEDLINE | ID: mdl-27333947
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Torsades de Pointes / Inhibidores de la Transcriptasa Inversa / Bloqueadores de los Canales de Potasio / Benzoxazinas / Citocromo P-450 CYP2B6 / Canal de Potasio ERG1 / Variantes Farmacogenómicas Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Revista: J Cardiovasc Electrophysiol Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Torsades de Pointes / Inhibidores de la Transcriptasa Inversa / Bloqueadores de los Canales de Potasio / Benzoxazinas / Citocromo P-450 CYP2B6 / Canal de Potasio ERG1 / Variantes Farmacogenómicas Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Revista: J Cardiovasc Electrophysiol Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Año: 2016 Tipo del documento: Article