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Gallium and Functionalized-Porphyrins Combine to Form Potential Lysosome-Specific Multimodal Bioprobes.
Pan, Jie; Harriss, Bethany I; Chan, Chi-Fai; Jiang, Lijun; Tsoi, Tik-Hung; Long, Nicholas J; Wong, Wing-Tak; Wong, Wai-Kwok; Wong, Ka-Leung.
Afiliación
  • Pan J; Department of Chemistry, Hong Kong Baptist University , Kowloon Tong, Kowloon, Hong Kong SAR.
  • Harriss BI; Department of Chemistry, Imperial College London, South Kensington Campus , London SW7 2AZ, United Kingdom.
  • Chan CF; Department of Chemistry, Hong Kong Baptist University , Kowloon Tong, Kowloon, Hong Kong SAR.
  • Jiang L; Department of Chemistry, Hong Kong Baptist University , Kowloon Tong, Kowloon, Hong Kong SAR.
  • Tsoi TH; Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University , Hung Hom, Hong Kong SAR.
  • Long NJ; Department of Chemistry, Imperial College London, South Kensington Campus , London SW7 2AZ, United Kingdom.
  • Wong WT; Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University , Hung Hom, Hong Kong SAR.
  • Wong WK; Department of Chemistry, Hong Kong Baptist University , Kowloon Tong, Kowloon, Hong Kong SAR.
  • Wong KL; Department of Chemistry, Hong Kong Baptist University , Kowloon Tong, Kowloon, Hong Kong SAR.
Inorg Chem ; 55(14): 6839-41, 2016 Jul 18.
Article en En | MEDLINE | ID: mdl-27355871
A water-soluble bimetallic normal ("cold") and radiochemical ("hot") gallium-porphyrin-ruthenium-bipyridine complex (GaporRu-1) has been synthesized by microwave methodology in short reaction times with good (>85%) yields. (68)GaporRu-1 is demonstrated to be a potential multimodal and functional bioprobe for positron emission tomography (PET), lysosome specific optical imaging, and photodynamic therapy.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Porfirinas / Sondas Moleculares / Galio / Lisosomas Idioma: En Revista: Inorg Chem Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Porfirinas / Sondas Moleculares / Galio / Lisosomas Idioma: En Revista: Inorg Chem Año: 2016 Tipo del documento: Article