Vitamin D and chronic diseases: the current state of the art.
Arch Toxicol
; 91(1): 97-107, 2017 Jan.
Article
en En
| MEDLINE
| ID: mdl-27425218
ABSTRACT
The objective was to provide the current state of the art regarding the role of vitamin D in chronic diseases (osteoporosis, cancer, cardiovascular diseases, dementia, autism, type 1 and type 2 diabetes mellitus, male and female fertility). The document was drawn up by panelists that provided their contribution according to their own scientific expertise. Each scientific expert supplied a first draft manuscript on a specific aspect of the document's topic that was subjected to voting by all experts as "yes" (agreement with the content and/or wording) or "no" (disagreement). The adopted rule was that statements supported by ≥75 % of votes would be immediately accepted, while those with <25 % would be rejected outright. Others would be subjected to further discussion and subsequent voting, where ≥67 % support or, in an eventual third round, a majority of ≥50 % would be needed. This document finds that the current evidence support a role for vitamin D in bone health but not in other health conditions. However, subjects with vitamin D deficiency have been found to be at high risk of developing chronic diseases. Therefore, although at the present time there is not sufficient evidence to recommend vitamin D supplementation as treatment of chronic diseases, the treatment of vitamin D deficiency should be desiderable in order to reduce the risk of developing chronic diseases.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Osteoporosis
/
Vitamina D
/
Deficiencia de Vitamina D
/
Medicina Basada en la Evidencia
Tipo de estudio:
Etiology_studies
/
Guideline
/
Risk_factors_studies
Idioma:
En
Revista:
Arch Toxicol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Italia