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GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.
Littlewood-Evans, Amanda; Sarret, Sophie; Apfel, Verena; Loesle, Perrine; Dawson, Janet; Zhang, Juan; Muller, Alban; Tigani, Bruno; Kneuer, Rainer; Patel, Saijel; Valeaux, Stephanie; Gommermann, Nina; Rubic-Schneider, Tina; Junt, Tobias; Carballido, José M.
Afiliación
  • Littlewood-Evans A; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland amanda.littlewood-evans@novartis.com.
  • Sarret S; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Apfel V; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Loesle P; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Dawson J; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Zhang J; Department of Analytical Science and Imaging, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Muller A; Department of Analytical Science and Imaging, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Tigani B; Global Imaging Group, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Kneuer R; Global Imaging Group, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Patel S; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Valeaux S; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Gommermann N; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Rubic-Schneider T; Preclinical Safety Division, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Junt T; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Carballido JM; Department of Autoimmunity Transplantation and Inflammation, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
J Exp Med ; 213(9): 1655-62, 2016 08 22.
Article en En | MEDLINE | ID: mdl-27481132
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Ácido Succínico / Receptores Acoplados a Proteínas G / Macrófagos Límite: Animals / Female / Humans Idioma: En Revista: J Exp Med Año: 2016 Tipo del documento: Article País de afiliación: Suiza
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Ácido Succínico / Receptores Acoplados a Proteínas G / Macrófagos Límite: Animals / Female / Humans Idioma: En Revista: J Exp Med Año: 2016 Tipo del documento: Article País de afiliación: Suiza