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Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
She, Qing-Bai; Gruvberger-Saal, Sofia K; Maurer, Matthew; Chen, Yilun; Jumppanen, Mervi; Su, Tao; Dendy, Meaghan; Lau, Ying-Ka Ingar; Memeo, Lorenzo; Horlings, Hugo M; van de Vijver, Marc J; Isola, Jorma; Hibshoosh, Hanina; Rosen, Neal; Parsons, Ramon; Saal, Lao H.
Afiliación
  • She QB; Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Gruvberger-Saal SK; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, USA.
  • Maurer M; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, KY, USA.
  • Chen Y; Division of Oncology and Pathology, Clinical Sciences, Lund University, Lund, Sweden.
  • Jumppanen M; Institute for Cancer Genetics, Columbia University Medical Center, New York, NY, USA.
  • Su T; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
  • Dendy M; Department of Medicine, Columbia University, New York, NY, USA.
  • Lau YK; Division of Oncology and Pathology, Clinical Sciences, Lund University, Lund, Sweden.
  • Memeo L; Department of Pathology, Seinäjoki Central Hospital, Seinäjoki, Finland.
  • Horlings HM; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
  • van de Vijver MJ; Institute for Cancer Genetics, Columbia University Medical Center, New York, NY, USA.
  • Isola J; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
  • Hibshoosh H; Department of Experimental Oncology, Mediterranean Institute of Oncology, Catania, Italy.
  • Rosen N; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Parsons R; Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands.
  • Saal LH; Institute of Medical Technology, University of Tampere, Tampere, Finland.
BMC Cancer ; 16: 587, 2016 08 02.
Article en En | MEDLINE | ID: mdl-27484095
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Inhibidores de Proteínas Quinasas / Redes Reguladoras de Genes / Mutación Tipo de estudio: Prognostic_studies Límite: Aged80 Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Inhibidores de Proteínas Quinasas / Redes Reguladoras de Genes / Mutación Tipo de estudio: Prognostic_studies Límite: Aged80 Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos