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Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing.
Hoang, Margaret L; Kinde, Isaac; Tomasetti, Cristian; McMahon, K Wyatt; Rosenquist, Thomas A; Grollman, Arthur P; Kinzler, Kenneth W; Vogelstein, Bert; Papadopoulos, Nickolas.
Afiliación
  • Hoang ML; Ludwig Center for Cancer Genetics and Therapeutics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; The Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, MD 21231;
  • Kinde I; Ludwig Center for Cancer Genetics and Therapeutics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; The Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, MD 21231;
  • Tomasetti C; Division of Biostatistics and Bioinformatics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21205; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205;
  • McMahon KW; Ludwig Center for Cancer Genetics and Therapeutics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; The Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, MD 21231;
  • Rosenquist TA; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794;
  • Grollman AP; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794; Department of Medicine, Stony Brook University, Stony Brook, NY 11794;
  • Kinzler KW; Ludwig Center for Cancer Genetics and Therapeutics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; bertvog@gmail.com kinzlke@jhmi.edu.
  • Vogelstein B; Ludwig Center for Cancer Genetics and Therapeutics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; The Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, MD 21231; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21231 bert
  • Papadopoulos N; Ludwig Center for Cancer Genetics and Therapeutics, Department of Oncology, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21231.
Proc Natl Acad Sci U S A ; 113(35): 9846-51, 2016 08 30.
Article en En | MEDLINE | ID: mdl-27528664
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Genoma Humano / Genómica / Secuenciación de Nucleótidos de Alto Rendimiento / Mutación Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Genoma Humano / Genómica / Secuenciación de Nucleótidos de Alto Rendimiento / Mutación Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article