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Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer.
Painter, Jodie N; O'Mara, Tracy A; Marquart, Louise; Webb, Penelope M; Attia, John; Medland, Sarah E; Cheng, Timothy; Dennis, Joe; Holliday, Elizabeth G; McEvoy, Mark; Scott, Rodney J; Ahmed, Shahana; Healey, Catherine S; Shah, Mitul; Gorman, Maggie; Martin, Lynn; Hodgson, Shirley V; Beckmann, Matthias W; Ekici, Arif B; Fasching, Peter A; Hein, Alexander; Rübner, Matthias; Czene, Kamila; Darabi, Hatef; Hall, Per; Li, Jingmei; Dörk, Thilo; Dürst, Matthias; Hillemanns, Peter; Runnebaum, Ingo B; Amant, Frederic; Annibali, Daniela; Depreeuw, Jeroen; Lambrechts, Diether; Neven, Patrick; Cunningham, Julie M; Dowdy, Sean C; Goode, Ellen L; Fridley, Brooke L; Winham, Stacey J; Njølstad, Tormund S; Salvesen, Helga B; Trovik, Jone; Werner, Henrica M J; Ashton, Katie A; Otton, Geoffrey; Proietto, Anthony; Mints, Miriam; Tham, Emma; Bolla, Manjeet K.
Afiliación
  • Painter JN; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • O'Mara TA; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Marquart L; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Attia J; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, Australia.
  • Medland SE; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Australia.
  • Cheng T; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Dennis J; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Holliday EG; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.
  • McEvoy M; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, Australia.
  • Scott RJ; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Australia.
  • Ahmed S; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Australia.
  • Healey CS; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, Australia.
  • Shah M; Hunter Area Pathology Service, John Hunter Hospital, Newcastle, Australia.
  • Gorman M; Centre for Information Based Medicine, University of Newcastle, Australia.
  • Martin L; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.
  • Hodgson SV; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.
  • Beckmann MW; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.
  • Ekici AB; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.
  • Fasching PA; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Hein A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Rübner M; Department of Clinical Genetics, St George's, University of London, London, United Kingdom.
  • Czene K; Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
  • Darabi H; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
  • Hall P; Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
  • Li J; Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California.
  • Dörk T; Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
  • Dürst M; Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
  • Hillemanns P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Runnebaum IB; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Amant F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Annibali D; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Depreeuw J; Hannover Medical School, Gynaecology Research Unit, Hannover, Germany.
  • Lambrechts D; Department of Gynaecology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
  • Neven P; Hannover Medical School, Clinics of Gynaecology and Obstetrics, Hannover, Germany.
  • Cunningham JM; Department of Gynaecology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
  • Dowdy SC; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals, KU Leuven - University of Leuven, Leuven, Belgium.
  • Goode EL; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals, KU Leuven - University of Leuven, Leuven, Belgium.
  • Fridley BL; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals, KU Leuven - University of Leuven, Leuven, Belgium.
  • Winham SJ; Vesalius Research Center, VIB, Leuven, Belgium.
  • Njølstad TS; Department of Oncology, Laboratory for Translational Genetics, University Hospitals Leuven, Leuven, Belgium.
  • Salvesen HB; Vesalius Research Center, VIB, Leuven, Belgium.
  • Trovik J; Department of Oncology, Laboratory for Translational Genetics, University Hospitals Leuven, Leuven, Belgium.
  • Werner HM; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals, KU Leuven - University of Leuven, Leuven, Belgium.
  • Ashton KA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
  • Otton G; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, Minnesota.
  • Proietto A; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
  • Mints M; Department of Biostatistics, University of Kansas Medical Center, Kansas City, Kansas.
  • Tham E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
  • Bolla MK; Department of Clinical Science, Centre for Cancer Biomarkers, The University of Bergen, Bergen, Norway.
Cancer Epidemiol Biomarkers Prev ; 25(11): 1503-1510, 2016 11.
Article en En | MEDLINE | ID: mdl-27550749
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Índice de Masa Corporal / Neoplasias Endometriales / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple / Análisis de la Aleatorización Mendeliana / Obesidad Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Female / Humans Idioma: En Revista: Cancer Epidemiol Biomarkers Prev Asunto de la revista: BIOQUIMICA / EPIDEMIOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Índice de Masa Corporal / Neoplasias Endometriales / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple / Análisis de la Aleatorización Mendeliana / Obesidad Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Female / Humans Idioma: En Revista: Cancer Epidemiol Biomarkers Prev Asunto de la revista: BIOQUIMICA / EPIDEMIOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Australia