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Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation.
McCracken, A N; McMonigle, R J; Tessier, J; Fransson, R; Perryman, M S; Chen, B; Keebaugh, A; Selwan, E; Barr, S A; Kim, S M; Roy, S G; Liu, G; Fallegger, D; Sernissi, L; Brandt, C; Moitessier, N; Snider, A J; Clare, S; Müschen, M; Huwiler, A; Kleinman, M T; Hanessian, S; Edinger, A L.
Afiliación
  • McCracken AN; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
  • McMonigle RJ; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
  • Tessier J; Department of Chemistry, Université de Montréal, Montreal, Quebec, Canada.
  • Fransson R; Department of Chemistry, Université de Montréal, Montreal, Quebec, Canada.
  • Perryman MS; Department of Chemistry, Université de Montréal, Montreal, Quebec, Canada.
  • Chen B; Department of Chemistry, Université de Montréal, Montreal, Quebec, Canada.
  • Keebaugh A; Department of Community and Environmental Medicine, School of Medicine, University of California, Irvine, CA, USA.
  • Selwan E; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
  • Barr SA; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
  • Kim SM; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
  • Roy SG; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
  • Liu G; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.
  • Fallegger D; Institute of Pharmacology, University of Bern, Bern, Switzerland.
  • Sernissi L; Department of Chemistry, Université de Montréal, Montreal, Quebec, Canada.
  • Brandt C; The Wellcome Trust Sanger Genome Campus, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
  • Moitessier N; Department of Chemistry, McGill University, Montréal, Québec, Canada.
  • Snider AJ; Cancer Center and Department of Medicine, Stony Brook University, Stony Brook, NY, USA.
  • Clare S; Northport Veterans Affairs Medical Center, Northport, NY, USA.
  • Müschen M; The Wellcome Trust Sanger Genome Campus, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
  • Huwiler A; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.
  • Kleinman MT; Institute of Pharmacology, University of Bern, Bern, Switzerland.
  • Hanessian S; Department of Community and Environmental Medicine, School of Medicine, University of California, Irvine, CA, USA.
  • Edinger AL; Department of Chemistry, Université de Montréal, Montreal, Quebec, Canada.
Leukemia ; 31(3): 669-677, 2017 03.
Article en En | MEDLINE | ID: mdl-27573555
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Lisoesfingolípidos / Clorhidrato de Fingolimod / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Lisoesfingolípidos / Clorhidrato de Fingolimod / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos