Association between perfluorooctanoic acid exposure and degranulation of mast cells in allergic inflammation.

Lee, Jun-Kyoung; Lee, Soyoung; Baek, Moon-Chang; Lee, Byung-Heon; Lee, Hyun-Shik; Kwon, Taeg Kyu; Park, Pil-Hoon; Shin, Tae-Yong; Khang, Dongwoo; Kim, Sang-Hyun

Lee, Jun-Kyoung; Lee, Soyoung; Baek, Moon-Chang; Lee, Byung-Heon; Lee, Hyun-Shik; Kwon, Taeg Kyu; Park, Pil-Hoon; Shin, Tae-Yong; Khang, Dongwoo; Kim, Sang-Hyun.

Afiliación

Lee JK; CMRI, Departments of Pharmacology, Kyungpook National University, Daegu, Republic of Korea.
Lee S; CMRI, Departments of Pharmacology, Kyungpook National University, Daegu, Republic of Korea.
Baek MC; Natural Product Research Center, Research Institute of Bioscience and Biotechnology, Jeongeup, Republic of Korea.
Lee BH; Molecular Medicine, Kyungpook National University, Daegu, Republic of Korea.
Lee HS; Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Kwon TK; School of Life Science, Kyungpook National University, Daegu, Republic of Korea.
Park PH; Department of Immunology, School of Medicine, Keimyung University, Daegu, Republic of Korea.
Shin TY; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Khang D; College of Pharmacy, Woosuk University, Jeonju, Republic of Korea.
Kim SH; Department of Physiology, School of Medicine, Gachon University, Incheon, Republic of Korea.

J Appl Toxicol ; 37(5): 554-562, 2017 05.

Article en En | MEDLINE | ID: mdl-27682001

Asunto(s)

Caprilatos/toxicidad; Degranulación de la Célula/efectos de los fármacos; Fluorocarburos/toxicidad; Hipersensibilidad/patología; Inflamación/patología; Mastocitos/efectos de los fármacos; Anafilaxia/inducido químicamente; Anafilaxia/patología; Animales; Calcio/metabolismo; Supervivencia Celular/efectos de los fármacos; Citocinas/biosíntesis; Liberación de Histamina/efectos de los fármacos; Inmunoglobulina E/inmunología; Fragmentos Fc de Inmunoglobulinas/metabolismo; Masculino; Mastocitos/patología; Ratones; Ratones Endogámicos ICR; beta-N-Acetilhexosaminidasas/metabolismo

Palabras clave

allergic inflammation; histamine; mast cells; perfluorooctanoic acid (PFOA); pro-inflammatory cytokine

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Caprilatos / Degranulación de la Célula / Fluorocarburos / Hipersensibilidad / Inflamación / Mastocitos Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: J Appl Toxicol Año: 2017 Tipo del documento: Article

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