Blockade of C5 in Severe Acute Postinfectious Glomerulonephritis Associated With Anti-Factor H Autoantibody.

Chehade, Hassib; Rotman, Samuel; Frémeaux-Bacchi, Véronique; Aubert, Vincent; Sadallah, Salima; Sifaki, Loukia; Salomon, Rémi; Pascual, Manuel

Chehade, Hassib; Rotman, Samuel; Frémeaux-Bacchi, Véronique; Aubert, Vincent; Sadallah, Salima; Sifaki, Loukia; Salomon, Rémi; Pascual, Manuel.

Afiliación

Chehade H; Pediatric Nephrology Unit, Service of Pediatrics, University Hospital of Lausanne (CHUV), Lausanne, Switzerland. Electronic address: hassib.chehade@chuv.ch.
Rotman S; Pathology Institute, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
Frémeaux-Bacchi V; Laboratory of Immunology and Biology, Hôpital Européen Georges-Pompidou, AP-HP, Paris, France.
Aubert V; Service of Immunology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
Sadallah S; Service of Immunology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
Sifaki L; Pediatric Nephrology Unit, Service of Pediatrics, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
Salomon R; Service of Pediatric Nephrology, Necker Children's Hospital, Paris, France.
Pascual M; Transplantation Center, University Hospital of Lausanne (CHUV), Lausanne, Switzerland. Electronic address: manuel.pascual@chuv.ch.

Am J Kidney Dis ; 68(6): 944-948, 2016 Dec.

Article en En | MEDLINE | ID: mdl-27683044

Asunto(s)

Anticuerpos Monoclonales Humanizados/uso terapéutico; Autoanticuerpos; Complemento C3/antagonistas & inhibidores; Factor H de Complemento/inmunología; Glomerulonefritis/tratamiento farmacológico; Glomerulonefritis/inmunología; Enfermedad Aguda; Niño; Glomerulonefritis/microbiología; Humanos; Masculino; Índice de Severidad de la Enfermedad

Palabras clave

CFH; Postinfectious glomerulonephritis (PIGN); acute kidney injury; anti-C5 monoclonal antibody; antifactor H autoantibody; case report; complement; crescentic PIGN; eculizumab; kidney function; pediatric; renal biopsy; terminal complement pathway blockade

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autoanticuerpos / Complemento C3 / Factor H de Complemento / Anticuerpos Monoclonales Humanizados / Glomerulonefritis Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Child / Humans / Male Idioma: En Revista: Am J Kidney Dis Año: 2016 Tipo del documento: Article

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