Direct interaction between miR-203 and ZEB2 suppresses epithelial-mesenchymal transition signaling and reduces lung adenocarcinoma chemoresistance.

Duan, Xunhuang; Fu, Zhaojian; Gao, Lingyuan; Zhou, Jin; Deng, Xiaojie; Luo, Xiaojun; Fang, Weiyi; Luo, Rongcheng

Duan, Xunhuang; Fu, Zhaojian; Gao, Lingyuan; Zhou, Jin; Deng, Xiaojie; Luo, Xiaojun; Fang, Weiyi; Luo, Rongcheng.

Afiliación

Duan X; Cancer Center, Traditional Chinese Medicine-Integrated Hospital, Southern Medical University, Guangzhou 510315, China.
Fu Z; Jiu Jiang NO. 1 People's Hospital, Jiujiang 332000, China.
Gao L; Cancer Research Institute, Southern Medical University, Guangzhou 510515, China.
Zhou J; Cancer Research Institute, Southern Medical University, Guangzhou 510515, China.
Deng X; Cancer Center, Traditional Chinese Medicine-Integrated Hospital, Southern Medical University, Guangzhou 510315, China.
Luo X; Cancer Center, Traditional Chinese Medicine-Integrated Hospital, Southern Medical University, Guangzhou 510315, China.
Fang W; Cancer Center, Traditional Chinese Medicine-Integrated Hospital, Southern Medical University, Guangzhou 510315, China.
Luo R; Cancer Center, Traditional Chinese Medicine-Integrated Hospital, Southern Medical University, Guangzhou 510315, China luorc01@163.com fangweiyi1975@163.com.

Acta Biochim Biophys Sin (Shanghai) ; 48(11): 1042-1049, 2016 Nov.

Article en En | MEDLINE | ID: mdl-27733346

Asunto(s)

Adenocarcinoma/patología; Transición Epitelial-Mesenquimal; Proteínas de Homeodominio/metabolismo; Neoplasias Pulmonares/patología; MicroARNs/metabolismo; Proteínas Represoras/metabolismo; Adenocarcinoma/metabolismo; Línea Celular Tumoral; Resistencia a Antineoplásicos; Técnicas de Silenciamiento del Gen; Proteínas de Homeodominio/genética; Humanos; Neoplasias Pulmonares/metabolismo; MicroARNs/genética; Regiones Promotoras Genéticas; Proteínas Represoras/genética; Transducción de Señal; Caja Homeótica 2 de Unión a E-Box con Dedos de Zinc

Palabras clave

ZEB2; lung adenocarcinoma; miR-203; tumor suppressor

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Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Adenocarcinoma / Proteínas de Homeodominio / MicroARNs / Transición Epitelial-Mesenquimal / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Acta Biochim Biophys Sin (Shanghai) Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2016 Tipo del documento: Article País de afiliación: China

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