Molecular Analysis of Hybrid Neurofibroma/Schwannoma Identifies Common Monosomy 22 and &#945;-T-Catenin/CTNNA3 as a Novel Candidate Tumor Suppressor.

Stahn, Verena; Nagel, Inga; Fischer-Huchzermeyer, Susan; Oyen, Florian; Schneppenheim, Reinhard; Gesk, Stefan; Bohring, Axel; Chikobava, Levan; Young, Peter; Gess, Burkhard; Werner, Mathias; Senner, Volker; Harder, Anja

Molecular Analysis of Hybrid Neurofibroma/Schwannoma Identifies Common Monosomy 22 and α-T-Catenin/CTNNA3 as a Novel Candidate Tumor Suppressor.

Stahn, Verena; Nagel, Inga; Fischer-Huchzermeyer, Susan; Oyen, Florian; Schneppenheim, Reinhard; Gesk, Stefan; Bohring, Axel; Chikobava, Levan; Young, Peter; Gess, Burkhard; Werner, Mathias; Senner, Volker; Harder, Anja.

Afiliación

Stahn V; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Nagel I; Institute of Human Genetics, University Hospital Schleswig-Holstein, Kiel, Germany.
Fischer-Huchzermeyer S; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Oyen F; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.
Schneppenheim R; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.
Gesk S; Institute of Human Genetics, University Hospital Schleswig-Holstein, Kiel, Germany.
Bohring A; Institute of Human Genetics, University Hospital Münster, Münster, Germany.
Chikobava L; Department of Sleep Medicine and Neuromuscular Disorders, University Hospital Münster, Münster, Germany.
Young P; Department of Sleep Medicine and Neuromuscular Disorders, University Hospital Münster, Münster, Germany.
Gess B; Institute of Pathology, Health Care Center, Brandenburg Hospital, Brandenburg Medical School Theodor Fontane, Brandenburg an der Havel, Germany.
Werner M; Institute of Pathology, HELIOS Klinikum Emil von Behring, Berlin, Germany.
Senner V; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Harder A; Institute of Neuropathology, University Hospital Münster, Münster, Germany; Institute of Pathology, Health Care Center, Brandenburg Hospital, Brandenburg Medical School Theodor Fontane, Brandenburg an der Havel, Germany. Electronic address: anja.harder@ukmuenster.de.

Am J Pathol ; 186(12): 3285-3296, 2016 12.

Article en En | MEDLINE | ID: mdl-27765635

Asunto(s)

Neoplasias de la Vaina del Nervio/genética; Neurilemoma/genética; Neurofibroma/genética; Neurofibromatosis/genética; Neurofibromatosis 1/genética; Neoplasias Cutáneas/genética; alfa Catenina/genética; Adolescente; Adulto; Anciano; Cromosomas Humanos Par 22/genética; Hibridación Genómica Comparativa; Transición Epitelial-Mesenquimal; Femenino; Humanos; Hibridación Fluorescente in Situ; Masculino; Persona de Mediana Edad; Monosomía; Neoplasias de la Vaina del Nervio/patología; Neurilemoma/patología; Neurofibroma/patología; Neurofibromatosis/patología; Neurofibromatosis 1/patología; Células de Schwann/metabolismo; Células de Schwann/patología; Neoplasias Cutáneas/patología; Proteínas Supresoras de Tumor/genética; Adulto Joven

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neurofibromatosis 1 / Neurofibromatosis / Neoplasias de la Vaina del Nervio / Alfa Catenina / Neurilemoma / Neurofibroma Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Pathol Año: 2016 Tipo del documento: Article País de afiliación: Alemania

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