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Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors.
Infante, Jeffrey R; Hollebecque, Antoine; Postel-Vinay, Sophie; Bauer, Todd M; Blackwood, Elizabeth M; Evangelista, Marie; Mahrus, Sami; Peale, Franklin V; Lu, Xuyang; Sahasranaman, Srikumar; Zhu, Rui; Chen, Yuan; Ding, Xiao; Murray, Elaine R; Schutzman, Jennifer L; Lauchle, Jennifer O; Soria, Jean-Charles; LoRusso, Patricia M.
Afiliación
  • Infante JR; Sarah Cannon Research Institute/Tennessee Oncology, Nashville, Tennessee. jinfante@tnonc.com.
  • Hollebecque A; Départemement d'Innovation Thérapeutique et des Essais Précoces (DITEP), Gustave Roussy, Université Paris Saclay, Villejuif, France.
  • Postel-Vinay S; Départemement d'Innovation Thérapeutique et des Essais Précoces (DITEP), Gustave Roussy, Université Paris Saclay, Villejuif, France.
  • Bauer TM; INSERM, U981, Villejuif, France.
  • Blackwood EM; Sarah Cannon Research Institute/Tennessee Oncology, Nashville, Tennessee.
  • Evangelista M; Genentech, Inc., South San Francisco, California.
  • Mahrus S; Genentech, Inc., South San Francisco, California.
  • Peale FV; Genentech, Inc., South San Francisco, California.
  • Lu X; Genentech, Inc., South San Francisco, California.
  • Sahasranaman S; Genentech, Inc., South San Francisco, California.
  • Zhu R; Genentech, Inc., South San Francisco, California.
  • Chen Y; Genentech, Inc., South San Francisco, California.
  • Ding X; Genentech, Inc., South San Francisco, California.
  • Murray ER; Genentech, Inc., South San Francisco, California.
  • Schutzman JL; Genentech, Inc., South San Francisco, California.
  • Lauchle JO; Genentech, Inc., South San Francisco, California.
  • Soria JC; Genentech, Inc., South San Francisco, California.
  • LoRusso PM; Départemement d'Innovation Thérapeutique et des Essais Précoces (DITEP), Gustave Roussy, Université Paris Saclay, Villejuif, France.
Clin Cancer Res ; 23(10): 2423-2432, 2017 May 15.
Article en En | MEDLINE | ID: mdl-27815358
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperidinas / Neoplasias de la Mama Triple Negativas / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) / Compuestos Heterocíclicos con 3 Anillos / Melanoma Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperidinas / Neoplasias de la Mama Triple Negativas / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) / Compuestos Heterocíclicos con 3 Anillos / Melanoma Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article