Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT<sub>2C</sub> receptor mediated appetite.

Garfield, Alastair S; Davies, Jennifer R; Burke, Luke K; Furby, Hannah V; Wilkinson, Lawrence S; Heisler, Lora K; Isles, Anthony R

Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT_2C receptor mediated appetite.

Garfield, Alastair S; Davies, Jennifer R; Burke, Luke K; Furby, Hannah V; Wilkinson, Lawrence S; Heisler, Lora K; Isles, Anthony R.

Afiliación

Garfield AS; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
Davies JR; Present address: Cardiovascular and Metabolic Disease, Pfizer, Cambridge, MA, 02139, USA.
Burke LK; Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Medicine and Pscyhology, Cardiff University, Cardiff, UK.
Furby HV; Department of Pharmacology, University of Cambridge, Cambridge, UK.
Wilkinson LS; Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Medicine and Pscyhology, Cardiff University, Cardiff, UK.
Heisler LK; Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Medicine and Pscyhology, Cardiff University, Cardiff, UK.
Isles AR; Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK.

Mol Brain ; 9(1): 95, 2016 12 08.

Article en En | MEDLINE | ID: mdl-27931246

Asunto(s)

Empalme Alternativo/genética; Apetito/genética; Síndrome de Prader-Willi/genética; Receptor de Serotonina 5-HT2C/genética; Animales; Anorexia/genética; Anorexia/patología; Núcleo Arqueado del Hipotálamo/efectos de los fármacos; Núcleo Arqueado del Hipotálamo/metabolismo; Núcleo Arqueado del Hipotálamo/patología; Secuencia de Bases; Modelos Animales de Enfermedad; Conducta Alimentaria; Ratones; Proteínas Mutantes/metabolismo; Neuronas/efectos de los fármacos; Neuronas/metabolismo; Síndrome de Prader-Willi/patología; Proopiomelanocortina/metabolismo; Proteínas Proto-Oncogénicas c-fos/metabolismo; Pirazinas/farmacología; Quinoxalinas/farmacología; Receptor de Serotonina 5-HT2C/metabolismo; Agonistas del Receptor de Serotonina 5-HT2/farmacología

Palabras clave

Alternate splicing; Feeding; Prader-Willi syndrome; Serotonin 2C recptor; Snord115

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Apetito / Síndrome de Prader-Willi / Empalme Alternativo / Receptor de Serotonina 5-HT2C Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Brain Asunto de la revista: BIOLOGIA MOLECULAR / CEREBRO Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido

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