Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis.

Parasuraman, Prasanna; Mulligan, Peter; Walker, James A; Li, Bihua; Boukhali, Myriam; Haas, Wilhelm; Bernards, Andre

Parasuraman, Prasanna; Mulligan, Peter; Walker, James A; Li, Bihua; Boukhali, Myriam; Haas, Wilhelm; Bernards, Andre.

Afiliación

Parasuraman P; From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129.
Mulligan P; From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129.
Walker JA; From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129.
Li B; From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129.
Boukhali M; From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129.
Haas W; From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129.
Bernards A; From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129 abernards@partners.org.

J Biol Chem ; 292(7): 2679-2689, 2017 02 17.

Article en En | MEDLINE | ID: mdl-28007963

Asunto(s)

Factor 3 de Iniciación Eucariótica/metabolismo; Factores de Intercambio de Guanina Nucleótido/metabolismo; Biosíntesis de Proteínas; Proteínas Represoras/metabolismo; Animales; Cromatografía de Afinidad; Factor 3 de Iniciación Eucariótica/química; Factor 3 de Iniciación Eucariótica/genética; Técnicas de Silenciamiento del Gen; Factores de Intercambio de Guanina Nucleótido/química; Factores de Intercambio de Guanina Nucleótido/genética; Células HeLa; Humanos; Ratones; Mutación Missense; Células 3T3 NIH; Unión Proteica; Proteínas Represoras/química; Proteínas Represoras/genética; Fracciones Subcelulares/metabolismo

Palabras clave

GTPase activating protein (GAP); Rho (Rho GTPase); cell biology; mass spectrometry (MS); protein biosynthesis; protein complexes; protein domains; translation ini; translation initiation factor; translational initiation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Biosíntesis de Proteínas / Factores de Intercambio de Guanina Nucleótido / Factor 3 de Iniciación Eucariótica Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2017 Tipo del documento: Article

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