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Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding.
Wong, Pancras C; Seiffert, Dietmar; Bird, J Eileen; Watson, Carol A; Bostwick, Jeffrey S; Giancarli, Mary; Allegretto, Nick; Hua, Ji; Harden, David; Guay, Jocelyne; Callejo, Mario; Miller, Michael M; Lawrence, R Michael; Banville, Jacques; Guy, Julia; Maxwell, Brad D; Priestley, E Scott; Marinier, Anne; Wexler, Ruth R; Bouvier, Michel; Gordon, David A; Schumacher, William A; Yang, Jing.
Afiliación
  • Wong PC; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA. pancras.wong@bms.com.
  • Seiffert D; Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, USA.
  • Bird JE; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Watson CA; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Bostwick JS; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Giancarli M; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Allegretto N; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Hua J; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Harden D; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Guay J; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.
  • Callejo M; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.
  • Miller MM; Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, USA.
  • Lawrence RM; Bristol-Myers Squibb Company, 350 Carter Road, Hopewell, NJ 08540, USA.
  • Banville J; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.
  • Guy J; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.
  • Maxwell BD; Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, USA.
  • Priestley ES; Bristol-Myers Squibb Company, 350 Carter Road, Hopewell, NJ 08540, USA.
  • Marinier A; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.
  • Wexler RR; Bristol-Myers Squibb Company, 350 Carter Road, Hopewell, NJ 08540, USA.
  • Bouvier M; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.
  • Gordon DA; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.
  • Schumacher WA; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
  • Yang J; Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534, USA.
Sci Transl Med ; 9(371)2017 01 04.
Article en En | MEDLINE | ID: mdl-28053157
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Agregación Plaquetaria / Receptores de Trombina / Fibrinolíticos / Hemorragia / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Agregación Plaquetaria / Receptores de Trombina / Fibrinolíticos / Hemorragia / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos