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Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
Guo, Chun-Jun; Chang, Fang-Yuan; Wyche, Thomas P; Backus, Keriann M; Acker, Timothy M; Funabashi, Masanori; Taketani, Mao; Donia, Mohamed S; Nayfach, Stephen; Pollard, Katherine S; Craik, Charles S; Cravatt, Benjamin F; Clardy, Jon; Voigt, Christopher A; Fischbach, Michael A.
Afiliación
  • Guo CJ; Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Chang FY; Department of Biological Engineering and Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02115, USA.
  • Wyche TP; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Backus KM; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92307, USA.
  • Acker TM; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Funabashi M; Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Taketani M; Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Donia MS; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
  • Nayfach S; Integrative Program in Quantitative Biology, Gladstone Institutes, and Division of Biostatistics, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Pollard KS; Integrative Program in Quantitative Biology, Gladstone Institutes, and Division of Biostatistics, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Craik CS; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Cravatt BF; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92307, USA.
  • Clardy J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Voigt CA; Department of Biological Engineering and Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02115, USA.
  • Fischbach MA; Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: fischbach@fischbachgroup.org.
Cell ; 168(3): 517-526.e18, 2017 01 26.
Article en En | MEDLINE | ID: mdl-28111075
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptido Sintasas / Pirazinas / Bacterias / Microbiota / Microbioma Gastrointestinal Límite: Animals / Humans Idioma: En Revista: Cell Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptido Sintasas / Pirazinas / Bacterias / Microbiota / Microbioma Gastrointestinal Límite: Animals / Humans Idioma: En Revista: Cell Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos