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Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening.
Jernigan, Finith E; Hanai, Jun-Ichi; Sukhatme, Vikas P; Sun, Lijun.
Afiliación
  • Jernigan FE; Center for Drug Discovery and Translational Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Hanai JI; Division of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Sukhatme VP; Division of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA;
  • Sun L; Center for Drug Discovery and Translational Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address: lsun1@bidmc.harvard.edu.
Bioorg Med Chem Lett ; 27(4): 929-935, 2017 02 15.
Article en En | MEDLINE | ID: mdl-28129980
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ATP Citrato (pro-S)-Liasa / Ácidos Carboxílicos / Inhibidores Enzimáticos / Furanos Tipo de estudio: Diagnostic_studies / Guideline / Screening_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ATP Citrato (pro-S)-Liasa / Ácidos Carboxílicos / Inhibidores Enzimáticos / Furanos Tipo de estudio: Diagnostic_studies / Guideline / Screening_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos