Probing the metabolic phenotype of breast cancer cells by multiple tracer stable isotope resolved metabolomics.

Lane, Andrew N; Tan, Julie; Wang, Yali; Yan, Jun; Higashi, Richard M; Fan, Teresa W-M

Lane, Andrew N; Tan, Julie; Wang, Yali; Yan, Jun; Higashi, Richard M; Fan, Teresa W-M.

Afiliación

Lane AN; J.G. Brown Cancer Center, University of Louisville, Louisville, KY, United States; Dept. Chemistry and Center for Regulatory and Environmental Analytical Metabolomics, University of Louisville, Louisville, KY, United States. Electronic address: andrew.lane@uky.edu.
Tan J; J.G. Brown Cancer Center, University of Louisville, Louisville, KY, United States. Electronic address: jinlian.tan@louisville.edu.
Wang Y; J.G. Brown Cancer Center, University of Louisville, Louisville, KY, United States. Electronic address: yali.wang@louisville.edu.
Yan J; J.G. Brown Cancer Center, University of Louisville, Louisville, KY, United States.
Higashi RM; Dept. Chemistry and Center for Regulatory and Environmental Analytical Metabolomics, University of Louisville, Louisville, KY, United States.
Fan TW; J.G. Brown Cancer Center, University of Louisville, Louisville, KY, United States; Dept. Chemistry and Center for Regulatory and Environmental Analytical Metabolomics, University of Louisville, Louisville, KY, United States. Electronic address: twmfan@gmail.com.

Metab Eng ; 43(Pt B): 125-136, 2017 09.

Article en En | MEDLINE | ID: mdl-28163219

Asunto(s)

Neoplasias de la Mama/metabolismo; Marcaje Isotópico/métodos; Redes y Vías Metabólicas; Metabolómica/métodos; Animales; Neoplasias de la Mama/patología; Femenino; Xenoinjertos; Humanos; Células MCF-7; Ratones; Ratones Endogámicos NOD; Ratones SCID; Trasplante de Neoplasias

Palabras clave

(13)C(3)-glycerol; (13)C(3)-glycerol (PubChem CID:753); (13)C(5); (13)C(5),(15)N(2)-Glutamine (PubChem CID:5961); (13)C(6)-glucose; (13)C(6)-glucose (PubChem CID:5793); (13)C(8)-octanoate; (13)C(8)-octanoate (PubChem CID:11939); (15)N(2)-Gln; (PubChem CID:5927); 1D/2D NMR; ATP; Breast cancer metabolism; FT-ICR-MS; Mouse xenografts; Stable isotope-resolved metabolomics; UTP(PubChem CID:6133); alanine (PubChem CID:5950); aspartate (PubChem CID:5460541); glutamate (PubChem CID:5128032); lactate (PubChem CID:91435)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Redes y Vías Metabólicas / Metabolómica / Marcaje Isotópico Límite: Animals / Female / Humans Idioma: En Revista: Metab Eng Asunto de la revista: ENGENHARIA BIOMEDICA / METABOLISMO Año: 2017 Tipo del documento: Article

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