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Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2.
Barnash, Kimberly D; The, Juliana; Norris-Drouin, Jacqueline L; Cholensky, Stephanie H; Worley, Beau M; Li, Fengling; Stuckey, Jacob I; Brown, Peter J; Vedadi, Masoud; Arrowsmith, Cheryl H; Frye, Stephen V; James, Lindsey I.
Afiliación
  • Barnash KD; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
  • The J; Structural Genomics Consortium, University of Toronto , Toronto, Ontario M5G 1L7, Canada.
  • Norris-Drouin JL; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
  • Cholensky SH; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
  • Worley BM; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
  • Li F; Structural Genomics Consortium, University of Toronto , Toronto, Ontario M5G 1L7, Canada.
  • Stuckey JI; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
  • Brown PJ; Structural Genomics Consortium, University of Toronto , Toronto, Ontario M5G 1L7, Canada.
  • Vedadi M; Structural Genomics Consortium, University of Toronto , Toronto, Ontario M5G 1L7, Canada.
  • Arrowsmith CH; Structural Genomics Consortium, University of Toronto , Toronto, Ontario M5G 1L7, Canada.
  • Frye SV; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto , Toronto, Ontario M5G 2M9, Canada.
  • James LI; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
ACS Comb Sci ; 19(3): 161-172, 2017 03 13.
Article en En | MEDLINE | ID: mdl-28165227
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación Alostérica / Peptidomiméticos / Complejo Represivo Polycomb 2 Límite: Humans Idioma: En Revista: ACS Comb Sci Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación Alostérica / Peptidomiméticos / Complejo Represivo Polycomb 2 Límite: Humans Idioma: En Revista: ACS Comb Sci Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos