Characterization of H type 1 and type 1 <i>N</i>-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4.

Choo, Matthew; Tan, Heng Liang; Ding, Vanessa; Castangia, Roberto; Belgacem, Omar; Liau, Brian; Hartley-Tassell, Lauren; Haslam, Stuart M; Dell, Anne; Choo, Andre

Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4.

Choo, Matthew; Tan, Heng Liang; Ding, Vanessa; Castangia, Roberto; Belgacem, Omar; Liau, Brian; Hartley-Tassell, Lauren; Haslam, Stuart M; Dell, Anne; Choo, Andre.

Afiliación

Choo M; From the Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Tan HL; the Bioprocessing Technology Institute, Singapore 138668, Singapore.
Ding V; the Bioprocessing Technology Institute, Singapore 138668, Singapore.
Castangia R; the Bioprocessing Technology Institute, Singapore 138668, Singapore.
Belgacem O; Shimadzu, Manchester M17 1GP, United Kingdom.
Liau B; Shimadzu, Manchester M17 1GP, United Kingdom.
Hartley-Tassell L; the Bioprocessing Technology Institute, Singapore 138668, Singapore.
Haslam SM; the Institute for Glycomics, Griffith University, Southport, Queensland 4215, Australia, and.
Dell A; From the Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Choo A; From the Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom, a.dell@imperial.ac.uk.

J Biol Chem ; 292(15): 6163-6176, 2017 04 14.

Article en En | MEDLINE | ID: mdl-28167527

Asunto(s)

Amino Azúcares/inmunología; Anticuerpos Monoclonales de Origen Murino/inmunología; Anticuerpos Antineoplásicos/inmunología; Antígenos de Neoplasias/inmunología; Epítopos/inmunología; Células Madre Neoplásicas/inmunología; Neoplasias Ováricas/inmunología; Neoplasias de la Mama/inmunología; Línea Celular Tumoral; Femenino; Humanos

Palabras clave

cancer biology; cancer therapy; embryonic stem cell; glycobiology; glycoconjugate; glycomics; mass spectrometry (MS); monoclonal antibody; ovarian cancer; small interfering RNA (siRNA)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Células Madre Neoplásicas / Anticuerpos Monoclonales de Origen Murino / Amino Azúcares / Anticuerpos Antineoplásicos / Epítopos / Antígenos de Neoplasias Límite: Female / Humans Idioma: En Revista: J Biol Chem Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido

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