Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel.

Negoda, Alexander; El Hiani, Yassine; Cowley, Elizabeth A; Linsdell, Paul

Negoda, Alexander; El Hiani, Yassine; Cowley, Elizabeth A; Linsdell, Paul.

Afiliación

Negoda A; Department of Physiology & Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada.
El Hiani Y; Department of Physiology & Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada.
Cowley EA; Department of Physiology & Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada.
Linsdell P; Department of Physiology & Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: paul.linsdell@dal.ca.

Biochim Biophys Acta Biomembr ; 1859(5): 1049-1058, 2017 May.

Article en En | MEDLINE | ID: mdl-28235470

Asunto(s)

Regulador de Conductancia de Transmembrana de Fibrosis Quística/química; Animales; Cricetinae; Regulador de Conductancia de Transmembrana de Fibrosis Quística/fisiología; Disulfuros/química; Ditiotreitol/farmacología; Leucina/química; Técnicas de Placa-Clamp

Palabras clave

Anion selectivity; Chloride channel; Cystic fibrosis transmembrane conductance regulator; Disulfide cross-linking; Ion channel pore; Selectivity filter

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulador de Conductancia de Transmembrana de Fibrosis Quística Límite: Animals Idioma: En Revista: Biochim Biophys Acta Biomembr Año: 2017 Tipo del documento: Article País de afiliación: Canadá

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