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A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.
Zhu, Mingzhao; Harshbarger, Wayne D; Robles, Omar; Krysiak, Joanna; Hull, Kenneth G; Cho, Sung Wook; Richardson, Robyn D; Yang, Yanyan; Garcia, Andres; Spiegelman, Lindsey; Ramirez, Bianca; Wilson, Christopher T; Yau, Ju Anne; Moore, James T; Walker, Caitlen B; Sacchettini, James C; Liu, Wenshe R; Sieber, Stephan A; Smith, Jeffrey W; Romo, Daniel.
Afiliación
  • Zhu M; Department of Chemistry & Biochemistry and CPRIT Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, TX 76706, USA.
  • Harshbarger WD; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA.
  • Robles O; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Krysiak J; Department of Chemistry, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany.
  • Hull KG; Department of Chemistry & Biochemistry and CPRIT Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, TX 76706, USA.
  • Cho SW; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Richardson RD; Sanford Burnham Medical Research Institute, La Jolla, CA, USA.
  • Yang Y; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Garcia A; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Spiegelman L; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Ramirez B; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Wilson CT; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Yau JA; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Moore JT; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Walker CB; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Sacchettini JC; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA.
  • Liu WR; Department of Chemistry, Texas A&M University, College Station, TX 77842, USA.
  • Sieber SA; Department of Chemistry, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany.
  • Smith JW; Sanford Burnham Medical Research Institute, La Jolla, CA, USA.
  • Romo D; Department of Chemistry & Biochemistry and CPRIT Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, TX 76706, USA. Electronic address: Daniel_Romo@baylor.edu.
Bioorg Med Chem ; 25(11): 2901-2916, 2017 06 01.
Article en En | MEDLINE | ID: mdl-28236510
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Complejo de la Endopetidasa Proteasomal / Ácido Graso Sintasas / Lactonas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Complejo de la Endopetidasa Proteasomal / Ácido Graso Sintasas / Lactonas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos