A Tandem Enzymatic sp<sup>2</sup> -C-Methylation Process: Coupling in Situ S-Adenosyl-l-Methionine Formation with Methyl Transfer.

Sadler, Joanna C; Humphreys, Luke D; Snajdrova, Radka; Burley, Glenn A

A Tandem Enzymatic sp² -C-Methylation Process: Coupling in Situ S-Adenosyl-l-Methionine Formation with Methyl Transfer.

Sadler, Joanna C; Humphreys, Luke D; Snajdrova, Radka; Burley, Glenn A.

Afiliación

Sadler JC; GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Humphreys LD; WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, UK.
Snajdrova R; GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Burley GA; Present address: Gilead Alberta ULC, 1021 Hayter Road NW, Edmonton, AB, T6S 1A1, Canada.

Chembiochem ; 18(11): 992-995, 2017 06 01.

Article en En | MEDLINE | ID: mdl-28371017

Asunto(s)

Metiltransferasas/metabolismo; S-Adenosilmetionina/metabolismo; Alquilación; Organismos Acuáticos; Bacterias/enzimología; Bacterias/metabolismo; Biocatálisis; Compuestos Heterocíclicos de Anillos Fusionados/metabolismo; Hidrocarburos Aromáticos/metabolismo; Marcaje Isotópico; Metilación

Palabras clave

S-adenosylmethionine; alkylation; biocatalysis; methyltransferase; multi-enzyme reaction

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: S-Adenosilmetionina / Metiltransferasas Idioma: En Revista: Chembiochem Asunto de la revista: BIOQUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido

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