Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitor FR901512.

Itoh, Hiroya; Matsui, Makoto; Kumagai, Toshitaka; Arita, Masanori; Machida, Masayuki; Shibata, Takashi

Itoh, Hiroya; Matsui, Makoto; Kumagai, Toshitaka; Arita, Masanori; Machida, Masayuki; Shibata, Takashi.

Afiliación

Itoh H; Biotechnology Labs, Astellas Pharma, Inc., Ibaraki, Japan hiroya.ito@astellas.com.
Matsui M; Technology Research Association of Highly Efficient Gene Design (TRAHED), Hokkaido, Japan.
Kumagai T; Biotechnology Labs, Astellas Pharma, Inc., Ibaraki, Japan.
Arita M; Technology Research Association of Highly Efficient Gene Design (TRAHED), Hokkaido, Japan.
Machida M; Technology Research Association of Highly Efficient Gene Design (TRAHED), Hokkaido, Japan.
Shibata T; Fermlab, Inc., Tokyo, Japan.

Genome Announc ; 5(14)2017 Apr 06.

Article en En | MEDLINE | ID: mdl-28385847

ABSTRACT

ABSTRACT

Fungal strain 14919 was originally isolated from a soil sample collected at Mt. Kiyosumi, Chiba Prefecture, Japan. It produces FR901512, a potent and strong 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The genome sequence of fungal strain 14919 was determined and annotated to improve the productivity of FR901512.

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Genome Announc Año: 2017 Tipo del documento: Article País de afiliación: Japón

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google