Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells.

Yan, Yun; Zhao, Wukui; Huang, Yikai; Tong, Huan; Xia, Yin; Jiang, Qing; Qin, Jinzhong

Yan, Yun; Zhao, Wukui; Huang, Yikai; Tong, Huan; Xia, Yin; Jiang, Qing; Qin, Jinzhong.

Afiliación

Yan Y; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, China.
Zhao W; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, China.
Huang Y; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, China.
Tong H; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, China.
Xia Y; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Jiang Q; Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing, China.
Qin J; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, China.

Sci Rep ; 7: 46276, 2017 04 10.

Article en En | MEDLINE | ID: mdl-28393894

Asunto(s)

Diferenciación Celular/genética; Células Madre Embrionarias/citología; Células Madre Embrionarias/metabolismo; Complejo Represivo Polycomb 1/deficiencia; Animales; Biomarcadores; Sistemas CRISPR-Cas; Línea Celular; Autorrenovación de las Células/genética; Técnicas de Inactivación de Genes; Marcación de Gen; Ratones; Modelos Biológicos; Células Madre Embrionarias de Ratones/citología; Células Madre Embrionarias de Ratones/metabolismo; Unión Proteica; Transactivadores/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diferenciación Celular / Células Madre Embrionarias / Complejo Represivo Polycomb 1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: China

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