Restricted access magnetic core-mesoporous shell microspheres with C8-modified interior pore walls for the identification of 20(S)-protopanaxadiol metabolites in rat plasma using UPLC-Q-TOF-MS/MS.

Ling, Jin; Yu, Yingjia; Feng, Jianan; Xu, Changjiang; Jiang, Jiebing; Wang, Liping; Long, Jiakun; Li, Yan; Duan, Gengli

Ling, Jin; Yu, Yingjia; Feng, Jianan; Xu, Changjiang; Jiang, Jiebing; Wang, Liping; Long, Jiakun; Li, Yan; Duan, Gengli.

Afiliación

Ling J; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China; Department of Pathology, Zhejiang Jinhua Guangfu Hospital, No. 1296 Huancheng North Road, Jinhua City, Zhejiang Province 321001, China.
Yu Y; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China.
Feng J; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China.
Xu C; Shanghai Innovative Research Center of Traditional Chinese Medicine, Shanghai 201203, China.
Jiang J; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China.
Wang L; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China.
Long J; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China.
Li Y; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China. Electronic address: yanli@fudan.edu.cn.
Duan G; Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai 201203, China. Electronic address: glduan@shmu.edu.cn.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1054: 73-79, 2017 Jun 01.

Article en En | MEDLINE | ID: mdl-28432922

Asunto(s)

Cromatografía Líquida de Alta Presión/métodos; Sapogeninas/sangre; Sapogeninas/metabolismo; Extracción en Fase Sólida/métodos; Espectrometría de Masas en Tándem/métodos; Animales; Óxido Ferrosoférrico/química; Microesferas; Porosidad; Ratas; Dióxido de Silicio/química

Palabras clave

20(S)-Protopanaxadiol; C8-modified interior pore-walls; Metabolite; Restricted access material; UPLC-Q-TOF

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sapogeninas / Cromatografía Líquida de Alta Presión / Espectrometría de Masas en Tándem / Extracción en Fase Sólida Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2017 Tipo del documento: Article País de afiliación: China

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