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MK2206 enhances the cytocidal effects of bufalin in multiple myeloma by inhibiting the AKT/mTOR pathway.
Xiang, Ru-Fang; Wang, Yan; Zhang, Nan; Xu, Wen-Bin; Cao, Yang; Tong, Jia; Li, Jun-Min; Wu, Ying-Li; Yan, Hua.
Afiliación
  • Xiang RF; Department of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China.
  • Wang Y; Department of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China.
  • Zhang N; Department of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China.
  • Xu WB; Department of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China.
  • Cao Y; Department of Hematology, The Third Affiliated Hospital of Suzhou University, The First People's Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China.
  • Tong J; Department of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China.
  • Li JM; Department of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China.
  • Wu YL; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Chemical Biology Division of Shanghai Universities E-Institutes, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medic
  • Yan H; Department of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China.
Cell Death Dis ; 8(5): e2776, 2017 05 11.
Article en En | MEDLINE | ID: mdl-28492559
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bufanólidos / Transducción de Señal / Proteínas Proto-Oncogénicas c-akt / Serina-Treonina Quinasas TOR / Compuestos Heterocíclicos con 3 Anillos / Mieloma Múltiple Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Death Dis Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bufanólidos / Transducción de Señal / Proteínas Proto-Oncogénicas c-akt / Serina-Treonina Quinasas TOR / Compuestos Heterocíclicos con 3 Anillos / Mieloma Múltiple Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Death Dis Año: 2017 Tipo del documento: Article País de afiliación: China