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Novel selective PDE type 1 inhibitors cause vasodilatation and lower blood pressure in rats.
Laursen, Morten; Beck, Lilliana; Kehler, Jan; Christoffersen, Claus Tornby; Bundgaard, Christoffer; Mogensen, Susie; Mow, Tomas Joachim; Pinilla, Estéfano; Knudsen, Jakob Schöllhammer; Hedegaard, Elise Røge; Grunnet, Morten; Simonsen, Ulf.
Afiliación
  • Laursen M; Lundbeck A/S, Copenhagen, Denmark.
  • Beck L; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.
  • Kehler J; Lundbeck A/S, Copenhagen, Denmark.
  • Christoffersen CT; Lundbeck A/S, Copenhagen, Denmark.
  • Bundgaard C; Lundbeck A/S, Copenhagen, Denmark.
  • Mogensen S; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.
  • Mow TJ; Lundbeck A/S, Copenhagen, Denmark.
  • Pinilla E; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.
  • Knudsen JS; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.
  • Hedegaard ER; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.
  • Grunnet M; Lundbeck A/S, Copenhagen, Denmark.
  • Simonsen U; Department of Drug Design and Pharmacology, Copenhagen University, Copenhagen, Denmark.
Br J Pharmacol ; 174(15): 2563-2575, 2017 08.
Article en En | MEDLINE | ID: mdl-28548283
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Fosfodiesterasa / Vasodilatación / Presión Sanguínea / Fosfodiesterasas de Nucleótidos Cíclicos Tipo 1 Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Dinamarca
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Fosfodiesterasa / Vasodilatación / Presión Sanguínea / Fosfodiesterasas de Nucleótidos Cíclicos Tipo 1 Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Dinamarca