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Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Strauch, Eva-Maria; Bernard, Steffen M; La, David; Bohn, Alan J; Lee, Peter S; Anderson, Caitlin E; Nieusma, Travis; Holstein, Carly A; Garcia, Natalie K; Hooper, Kathryn A; Ravichandran, Rashmi; Nelson, Jorgen W; Sheffler, William; Bloom, Jesse D; Lee, Kelly K; Ward, Andrew B; Yager, Paul; Fuller, Deborah H; Wilson, Ian A; Baker, David.
Afiliación
  • Strauch EM; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Bernard SM; Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • La D; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Bohn AJ; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Lee PS; Department of Microbiology, University of Washington, Seattle, Washington, USA.
  • Anderson CE; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Nieusma T; Department of Bioengineering, University of Washington, Seattle, Washington, USA.
  • Holstein CA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Garcia NK; Department of Bioengineering, University of Washington, Seattle, Washington, USA.
  • Hooper KA; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, USA.
  • Ravichandran R; Division of Basic Sciences and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Nelson JW; Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Sheffler W; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Bloom JD; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Lee KK; Division of Basic Sciences and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Ward AB; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, USA.
  • Yager P; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Fuller DH; Department of Bioengineering, University of Washington, Seattle, Washington, USA.
  • Wilson IA; Department of Microbiology, University of Washington, Seattle, Washington, USA.
  • Baker D; Washington National Primate Research Center, University of Washington, Seattle, Washington, USA.
Nat Biotechnol ; 35(7): 667-671, 2017 Jul.
Article en En | MEDLINE | ID: mdl-28604661
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Glicoproteínas Hemaglutininas del Virus de la Influenza / Multimerización de Proteína / Simulación del Acoplamiento Molecular / Modelos Químicos Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Glicoproteínas Hemaglutininas del Virus de la Influenza / Multimerización de Proteína / Simulación del Acoplamiento Molecular / Modelos Químicos Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos