Three mutations switch H7N9 influenza to human-type receptor specificity.

de Vries, Robert P; Peng, Wenjie; Grant, Oliver C; Thompson, Andrew J; Zhu, Xueyong; Bouwman, Kim M; de la Pena, Alba T Torrents; van Breemen, Marielle J; Ambepitiya Wickramasinghe, Iresha N; de Haan, Cornelis A M; Yu, Wenli; McBride, Ryan; Sanders, Rogier W; Woods, Robert J; Verheije, Monique H; Wilson, Ian A; Paulson, James C

de Vries, Robert P; Peng, Wenjie; Grant, Oliver C; Thompson, Andrew J; Zhu, Xueyong; Bouwman, Kim M; de la Pena, Alba T Torrents; van Breemen, Marielle J; Ambepitiya Wickramasinghe, Iresha N; de Haan, Cornelis A M; Yu, Wenli; McBride, Ryan; Sanders, Rogier W; Woods, Robert J; Verheije, Monique H; Wilson, Ian A; Paulson, James C.

Afiliación

de Vries RP; Departments of Molecular Medicine, & Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States of America.
Peng W; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, CG Utrecht, The Netherlands.
Grant OC; Departments of Molecular Medicine, & Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States of America.
Thompson AJ; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, United States of America.
Zhu X; Departments of Molecular Medicine, & Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States of America.
Bouwman KM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States of America.
de la Pena ATT; Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, CL Utrecht, The Netherlands.
van Breemen MJ; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, AZ Amsterdam, The Netherlands.
Ambepitiya Wickramasinghe IN; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, AZ Amsterdam, The Netherlands.
de Haan CAM; Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, CL Utrecht, The Netherlands.
Yu W; Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1,CL Utrecht, The Netherlands.
McBride R; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States of America.
Sanders RW; Departments of Molecular Medicine, & Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States of America.
Woods RJ; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, AZ Amsterdam, The Netherlands.
Verheije MH; Department of Microbiology and Immunology, Weil Medical College of Cornell University, New York, NY, United States of America.
Wilson IA; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, United States of America.
Paulson JC; Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, CL Utrecht, The Netherlands.

PLoS Pathog ; 13(6): e1006390, 2017 Jun.

Article en En | MEDLINE | ID: mdl-28617868

Asunto(s)

Glicoproteínas Hemaglutininas del Virus de la Influenza/genética; Subtipo H7N9 del Virus de la Influenza A/genética; Gripe Aviar/virología; Gripe Humana/virología; Enfermedades de las Aves de Corral/virología; Secuencia de Aminoácidos; Animales; Glicoproteínas Hemaglutininas del Virus de la Influenza/química; Glicoproteínas Hemaglutininas del Virus de la Influenza/metabolismo; Especificidad del Huésped; Humanos; Subtipo H3N2 del Virus de la Influenza A/química; Subtipo H3N2 del Virus de la Influenza A/genética; Subtipo H3N2 del Virus de la Influenza A/metabolismo; Subtipo H7N9 del Virus de la Influenza A/química; Subtipo H7N9 del Virus de la Influenza A/metabolismo; Gripe Aviar/genética; Gripe Aviar/metabolismo; Gripe Humana/genética; Gripe Humana/metabolismo; Datos de Secuencia Molecular; Mutación; Aves de Corral; Enfermedades de las Aves de Corral/genética; Enfermedades de las Aves de Corral/metabolismo; Unión Proteica; Receptores Virales/genética; Receptores Virales/metabolismo; Alineación de Secuencia

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades de las Aves de Corral / Glicoproteínas Hemaglutininas del Virus de la Influenza / Gripe Humana / Subtipo H7N9 del Virus de la Influenza A / Gripe Aviar Límite: Animals / Humans Idioma: En Revista: PLoS Pathog Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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