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Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.
Broeckel, Rebecca; Fox, Julie M; Haese, Nicole; Kreklywich, Craig N; Sukulpovi-Petty, Soila; Legasse, Alfred; Smith, Patricia P; Denton, Michael; Corvey, Carsten; Krishnan, Shiv; Colgin, Lois M A; Ducore, Rebecca M; Lewis, Anne D; Axthelm, Michael K; Mandron, Marie; Cortez, Pierre; Rothblatt, Jonathan; Rao, Ercole; Focken, Ingo; Carter, Kara; Sapparapau, Gopal; Crowe, James E; Diamond, Michael S; Streblow, Daniel N.
Afiliación
  • Broeckel R; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, United States of America.
  • Fox JM; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, United States of America.
  • Haese N; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, United States of America.
  • Kreklywich CN; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, United States of America.
  • Sukulpovi-Petty S; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, United States of America.
  • Legasse A; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Beaverton, United States of America.
  • Smith PP; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, United States of America.
  • Denton M; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, United States of America.
  • Corvey C; Sanofi, Cambridge, United States of America.
  • Krishnan S; Sanofi, Cambridge, United States of America.
  • Colgin LMA; Pathology Services Unit, Division of Comparative Medicine, Oregon National Primate Research Center, Beaverton, United States of America.
  • Ducore RM; Pathology Services Unit, Division of Comparative Medicine, Oregon National Primate Research Center, Beaverton, United States of America.
  • Lewis AD; Pathology Services Unit, Division of Comparative Medicine, Oregon National Primate Research Center, Beaverton, United States of America.
  • Axthelm MK; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, United States of America.
  • Mandron M; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Beaverton, United States of America.
  • Cortez P; Sanofi, Marcy L'Etoile, France.
  • Rothblatt J; Sanofi, Marcy L'Etoile, France.
  • Rao E; Sanofi, Cambridge, United States of America.
  • Focken I; Sanofi, Marcy L'Etoile, France.
  • Carter K; Sanofi, Marcy L'Etoile, France.
  • Sapparapau G; Sanofi, Cambridge, United States of America.
  • Crowe JE; Departments of Pediatrics and Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, United States of America.
  • Diamond MS; Departments of Pediatrics and Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, United States of America.
  • Streblow DN; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, United States of America.
PLoS Negl Trop Dis ; 11(6): e0005637, 2017 Jun.
Article en En | MEDLINE | ID: mdl-28628616
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fiebre Chikungunya / Factores Inmunológicos / Anticuerpos Monoclonales / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Negl Trop Dis Asunto de la revista: MEDICINA TROPICAL Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fiebre Chikungunya / Factores Inmunológicos / Anticuerpos Monoclonales / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Negl Trop Dis Asunto de la revista: MEDICINA TROPICAL Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos