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Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
Kalia, Nitin P; Hasenoehrl, Erik J; Ab Rahman, Nurlilah B; Koh, Vanessa H; Ang, Michelle L T; Sajorda, Dannah R; Hards, Kiel; Grüber, Gerhard; Alonso, Sylvie; Cook, Gregory M; Berney, Michael; Pethe, Kevin.
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  • Kalia NP; Lee Kong Chian School of Medicine and School of Biological Sciences, Nanyang Technological University, Singapore 636921.
  • Hasenoehrl EJ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
  • Ab Rahman NB; Lee Kong Chian School of Medicine and School of Biological Sciences, Nanyang Technological University, Singapore 636921.
  • Koh VH; Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117456.
  • Ang MLT; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore 117456.
  • Sajorda DR; Lee Kong Chian School of Medicine and School of Biological Sciences, Nanyang Technological University, Singapore 636921.
  • Hards K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
  • Grüber G; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.
  • Alonso S; School of Biological Sciences, Nanyang Technological University, Singapore 637551.
  • Cook GM; Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117456.
  • Berney M; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore 117456.
  • Pethe K; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, 9054 Dunedin, New Zealand.
Proc Natl Acad Sci U S A ; 114(28): 7426-7431, 2017 07 11.
Article en En | MEDLINE | ID: mdl-28652330
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Mutaciones Letales Sintéticas / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Mutaciones Letales Sintéticas / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article